ArticleEcancermedicalscience2021
African American participation in cancer clinical trials.
Article in Ecancermedicalscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Patient perspective of Hesitancies and strategies to increase cancer clinical trial participation.Journal of clinical and translational science · 2026Article
- Barriers and Facilitators to Cancer Clinical Trial Participation: Perspectives of Patients in the ICON-3 Practice-Based Research Network, Nigeria.JCO global oncology · 2025Article
- A Proposal for Addressing Bioethical Concerns Along the 10-Step Framework for Community Engagement.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- Racial Differences in ctDNA Profiles, Targeted Therapy Use, and Outcomes in Metastatic Breast Cancer.JAMA network open · 2025Article
- Optimizing Recruitment and Retention in Cancer Clinical Trials in Low-Resource Settings: Barriers and Facilitators From Nigerian Provider's Perspectives.JCO global oncology · 2025Article
- How to optimize and evaluate diversity in gynecologic cancer clinical trials: statements from the GCIG Barcelona Meeting.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2024Article
- Breast cancer clinical trial participation among diverse patients at a comprehensive cancer center.NPJ breast cancer · 2024Article
- Primary care patient interests in joining a planned multi-cancer early detection clinical trial.Cancer medicine · 2024Article
- Involvement of Diverse Populations in Transfusion Medicine Research.Transfusion medicine reviews · 2023Article
- Accounting for the High Enrollment of African Americans on Winship Cancer Institute's Myeloma Clinical Trials.Ethics, medicine, and public health · 2023Article
- Article
- Ensuring equitable access to cancer care for Black patients in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2022Article
- An evaluation of race-based representation among men participating in clinical trials for prostate cancer and erectile dysfunction.Contemporary clinical trials communications · 2022Article
- Disparities in awareness of and willingness to participate in cancer clinical trials between African American and White cancer survivors.BMC cancer · 2022Article
- Sarcoidosis: Updates on therapeutic drug trials and novel treatment approaches.Frontiers in medicine · 2022Review
- Bridging the Gap: A Community Advisory Board Promoting Community Engagement in Cancer Research for Ethnically Diverse Populations.American journal of men's healthArticle
- Partnering With Faith Communities to Increase Knowledge of Precision Medicine and Genetic Research in the Black Community.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAccording to the Food and Drug Administration, African Americans (AAs) have been habitually underrepresented in cancer clinical trials (CCTs). This under-enrolment has contributed to cancer disparities despite the implementation of policies to improve AA accrual. This systematic review aimed to determine (1) Why AAs are participating in CCT at lower rates compared to other ethnic/racial groups and (2) Are there any tools that have definitively improved AA participation or addressed the barriers associated with their lack of participation.
methodsSearches were carried out in PubMed, Project MUSE and EBSCO which were confined to four databases (BASE, PsycINFO, CINAHL and MEDLINE). Literature published between 2010 and 2020 were filtered with the inclusion and exclusion criteria and then a mixed methods appraisal tool was used to check the quality of the articles. Studies were separated into two categories to extract and synthesise data based on the emerging themes.
resultsFrequent reasons for a lack of participation involved provider related issues, family concerns, health literacy and trust among others. Interventions cited as successful in improving AA participation or addressing a barrier often revolved around community-based participatory research and educational CCT videos/tools. RECOMMENDATIONS/
conclusionEducating AA patients about the biomedical research process, addressing concerns about CCTs, building trust with community members and improving communication with healthcare providers could improve AA participation in CCTs. Future interventions should consider the effect of diversified healthcare teams in addressing trust deficit in CCTs among AAs. Healthcare practitioners seeking to consent AA into CCTs and biomedical research could consider incorporating cultural competence into their practice for effective interaction with this population and to address their questions about biomedical research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.