Evidence map›Paper›PMID 34824594›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

The Anti-Inflammatory Effect of

Siyi Jiang, Qiong Wei, Xiaochuan Ye, Dan Luo, Xiaoyan Zhang, Zhenglei Li, Pengtao You, Xianzhang Huang, Yanwen Liu

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Antimicrobial Activity ofMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Siyi JiangCollege of Pharmacy of Hubei University of Chinese Medicine, Wuhan, Hubei 430061, China.
Qiong WeiCollege of Pharmacy of Hubei University of Chinese Medicine, Wuhan, Hubei 430061, China.
Xiaochuan YeCollege of Pharmacy of Hubei University of Chinese Medicine, Wuhan, Hubei 430061, China.ORCID https://orcid.org/0000-0003-4328-478X
Dan LuoCollege of Pharmacy of Hubei University of Chinese Medicine, Wuhan, Hubei 430061, China.
Xiaoyan ZhangCollege of Pharmacy of Hubei University of Chinese Medicine, Wuhan, Hubei 430061, China.
Zhenglei LiCollege of Pharmacy of Hubei University of Chinese Medicine, Wuhan, Hubei 430061, China.
Pengtao YouCollege of Pharmacy of Hubei University of Chinese Medicine, Wuhan, Hubei 430061, China.ORCID https://orcid.org/0000-0001-9466-2344
Xianzhang HuangHenan Key Laboratory of Zhang Zhongjing Formulae and Herbs for Immunoregulation, Nanyang Institute of Technology, Nanyang 473004, China.
Yanwen LiuCollege of Pharmacy of Hubei University of Chinese Medicine, Wuhan, Hubei 430061, China.
Hubei University of Chinese Medicine · CNNanyang Institute of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTraditional Chinese medicine Smilax is the rhizome of liliaceous plant PURPOSE: To investigate the mechanism of anti-inflammatory activity of the extract from

methodsThe components of ES were identified by UPLC-QTOF-MS/MS. The anti-inflammatory activities were evaluated in xylene-induced ear oedema and egg white-induced plantar swelling test. Cell viability was examined by CCK-8 assay. The inflammatory mediators, proinflammatory cytokines, and MAPK and NF-

results20 compounds of ES were confirmed by comparing with the reference substance. ES displayed more prominent anti-inflammatory activity than the positive control "Jin Gang Teng" capsule in the

conclusionThe results suggested that ES could selectively inhibit the activity of COX-2, and the anti-inflammatory effect of ES was associated with the inhibition of IL-1

Identifiers

PMID34824594
PMCPMC8610668
OpenAlexW3214419173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.