Evidence map›Paper›PMID 34824531›Full record

ArticleInternational journal of nanomedicine2021

Graphene Oxide-Copper Nanocomposites Suppress Cariogenic

Mengying Mao, Wenjie Zhang, Zhengwei Huang, Jing Huang, Jia Wang, Weiping Li, Shensheng Gu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Article
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  10. Article
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  12. Copper Materials for Caries Management: A Scoping Review.Journal of functional biomaterials · 2023
    Article
  13. Article
  14. SrCuSiAdvanced healthcare materials · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mengying MaoDepartment of Endodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Wenjie ZhangNational Clinical Research Center for Oral Diseases, Shanghai, People's Republic of China.
Zhengwei HuangDepartment of Endodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Jing HuangDepartment of Endodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Jia WangDepartment of Endodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Weiping LiDepartment of Endodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Shensheng GuDepartment of Endodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDental caries is a biofilm-dependent disease that largely relies on the ability of

methodsGrowth curve observation and colony forming units counting were applied to detect the antibacterial effect of GO-Cu nanocomposites on

resultsIt has been found that GO-Gu nanocomposites were antibacterial to

conclusionIn all, we found low-dose GO-Cu nanocomposites could disrupt exopolysaccharide matrix assembly and further impair optimal biofilm development with minimal cytotoxicity. Therefore, GO-Cu nanocomposites can open up a new avenue for the development of alternative anti-caries biomaterials.

Indexed as

Dental CariesGraphiteNanocompositesAnti-Bacterial AgentsBiofilmsCariostatic AgentsCopperHumansStreptococcus mutansAnti-Bacterial AgentsCariostatic AgentsCoppergraphene oxideGraphiteanti-biofilmdental cariesexopolysaccharidesgraphene oxide-copper nanocompositesStreptococcus mutans

Identifiers

PMID34824531
PMCPMC8610231

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.