ArticleCommunications biology2021
Effects of poor sleep on the immune cell landscape as assessed by single-cell analysis.
Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed, 51 citations in OpenAlex.
- Peripheral and central immune features in insomnia: Integrative bulk and single-cell transcriptomic analyses reveal core hub genes and candidate compounds.Functional & integrative genomics · 2026Article
- Integrated single-cell transcriptomic analysis identifiesBiochemistry and biophysics reports · 2026Article
- Sleep and circadian rhythms in cardiovascular resilience: mechanisms, implications, and a Roadmap for research and interventions.Nature reviews. Cardiology · 2026Review
- The Influence of Sleep and Diet on Human Peripheral Immunity and Chronic Health Conditions.Research (Washington, D.C.) · 2026Article
- Gastrodin improves learning and memory in sleep-deprived mice through suppression of ferroptosis in hippocampal neurons via Nrf2.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Sleep disorders in hepatocellular carcinoma.World journal of gastrointestinal oncology · 2025Review
- Sleep mediates the association between stroke and all cause mortality in the NHANES cohort.Scientific reports · 2025Article
- Article
- Association Between Dietary Magnesium Intake and Sleep Quality in Saudi University Students: A Cross-Sectional Study.Nature and science of sleep · 2025Article
- A dynamic peripheral immune landscape during human pregnancy.Fundamental research · 2025Article
- Short sleep time has a greater impact on the gut microbiota of female.Sleep & breathing = Schlaf & Atmung · 2024Article
- Association between sleep traits and risk of colorectal cancer: a bidirectional Mendelian randomization study.Journal of gastrointestinal oncology · 2024Article
- Decoding Cancer Risk: Understanding Gene-Environment Interactions in Cancer Development.Cureus · 2024Review
- Effect of Obstructive Sleep Apnea during Pregnancy on Fetal Development: Gene Expression Profile of Cord Blood.International journal of molecular sciences · 2024Article
- Retrospective Case Study on the Evaluation of Inflammatory Markers, Macrophage Inhibitory Protein-1α and Interferon-γ in Sleep Deprivation Condition.Journal of pharmacy & bioallied sciences · 2024Article
- The effect of the interaction of sleep onset latency and age on ischemic stroke severity via inflammatory chemokines.Frontiers in neurology · 2024Article
- Exploring shared biomarkers and shared pathways in insomnia and atherosclerosis using integrated bioinformatics analysis.Frontiers in molecular neuroscience · 2024Article
- Traumatic brain injury and sleep in military and veteran populations: A literature review.NeuroRehabilitation · 2024Review
- Investigation on sleep quality and psychological distress in patients with pulmonary nodules.BMC psychology · 2023Article
- Circadian disruption and psychostimulants dysregulates plasma acute-phase proteins and circulating cell-free mitochondrial DNA.Brain, behavior, & immunity - health · 2023Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poor sleep has become an important public health issue. With loss of sleep durations, poor sleep has been linked to the increased risks for diseases. Here we employed mass cytometry and single-cell RNA sequencing to obtain a comprehensive human immune cells landscape in the context of poor sleep, which was analyzed in the context of subset composition, gene signatures, enriched pathways, transcriptional regulatory networks, and intercellular interactions. Participants subjected to staying up had increased T and plasma cell frequency, along with upregulated autoimmune-related markers and pathways in CD4
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.