ArticleNature ecology & evolution2022
The earliest Denisovans and their cultural adaptation.
Article in Nature ecology & evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 51 citations in OpenAlex.
- Article
- Article
- A high-coverage Neandertal genome from the Altai Mountains reveals population structure among Neandertals.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- The Impact of Cooperation Under Climate Constraints: An Agent-Based Model for Exploring Paleolithic Behavioral Adaptations in the Inner Asian Mountain Corridor.Journal of archaeological method and theory · 2026Article
- A library of avian proteins improves palaeoproteomic taxonomic identification and reveals widespread intraspecies variability.Nature communications · 2025Article
- Candidate Denisovan fossils identified through gene regulatory phenotyping.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Pleistocene chronology and history of hominins and fauna at Denisova Cave.Nature communications · 2025Article
- A history of multiple Denisovan introgression events in modern humans.Nature genetics · 2024Review
- SpecieScan: semi-automated taxonomic identification of bone collagen peptides from MALDI-ToF-MS.Bioinformatics (Oxford, England) · 2024Article
- More than a decade of genetic research on the Denisovans.Nature reviews. Genetics · 2024Review
- Review
- Operationalizing cultural adaptation to climate change: contemporary examples from United States agriculture.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Predicting Archaic Hominin Phenotypes from Genomic Data.Annual review of genomics and human genetics · 2022Review
- A primer for ZooMS applications in archaeology.Proceedings of the National Academy of Sciences of the United States of America · 2022Review
- Microstratigraphic preservation of ancient faunal and hominin DNA in Pleistocene cave sediments.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
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Authors and funding
12 authors at 4 institutions in 4 countries.
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Abstract
Since the initial identification of the Denisovans a decade ago, only a handful of their physical remains have been discovered. Here we analysed ~3,800 non-diagnostic bone fragments using collagen peptide mass fingerprinting to locate new hominin remains from Denisova Cave (Siberia, Russia). We identified five new hominin bones, four of which contained sufficient DNA for mitochondrial analysis. Three carry mitochondrial DNA of the Denisovan type and one was found to carry mtDNA of the Neanderthal type. The former come from the same archaeological layer near the base of the cave's sequence and are the oldest securely dated evidence of Denisovans at 200 ka (thousand years ago) (205-192 ka at 68.2% or 217-187 ka at 95% probability). The stratigraphic context in which they were located contains a wealth of archaeological material in the form of lithics and faunal remains, allowing us to determine the material culture associated with these early hominins and explore their behavioural and environmental adaptations. The combination of bone collagen fingerprinting and genetic analyses has so far more-than-doubled the number of hominin bones at Denisova Cave and has expanded our understanding of Denisovan and Neanderthal interactions, as well as their archaeological signatures.
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