Evidence map›Paper›PMID 34824350›Full record

ArticleCommunications biology2021

A cell-based multiplex immunoassay platform using fluorescent protein-barcoded reporter cell lines.

Shengli Song, Miriam Manook, Jean Kwun, Annette M Jackson, Stuart J Knechtle, Garnett Kelsoe

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. A novel immunoglobulin G- and immunoglobulin cleaving enzyme MG (IceMG), for antibody-mediated rejection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Protective human antibodies against a conserved epitope in pre- and postfusion influenza hemagglutinin.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Shengli SongDepartment of Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Miriam ManookDepartment of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-6474-6122
Jean KwunDepartment of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-8563-5472
Annette M JacksonDepartment of Immunology, Duke University School of Medicine, Durham, North Carolina, USA.
Stuart J KnechtleDepartment of Surgery, Duke University School of Medicine, Durham, North Carolina, USA.ORCID 0000-0002-1625-385X
Garnett KelsoeDepartment of Immunology, Duke University School of Medicine, Durham, North Carolina, USA. garnett.kelsoe@duke.edu.ORCID 0000-0002-8770-040X
Duke University · US

Funding

Virology CoreP01AI089618 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI STEPHEN COPLAN HARRISON · 2011 to 2026
$40.0M
Immunity to novel T/F SHIVs: variability in the co-evolution of virus and host immunityR01AI128832 · NIAID · DUKE UNIVERSITY · PI KELSOE, GARNETT H · 2017 to 2021
$5.4M
NIAID NIH HHS P01 AI089618NIAID NIH HHS R01 AI128832
6 · The paper itself

Abstract

Multiplex immunoassays with acellular antigens are well-established based on solid-phase platforms such as the Luminex

Indexed as

Flow CytometryAntibodiesCell LineEpitopesFluorescent DyesHemagglutininsImmunoassayInfluenza A virusMembrane ProteinsMutationProtein MultimerizationReceptors, CCR2Receptors, CCR5AntibodiesCCR2 protein, humanCCR5 protein, humanEpitopesFluorescent DyesHemagglutininsMembrane ProteinsReceptors, CCR2Receptors, CCR5

Identifiers

PMID34824350
PMCPMC8617053
OpenAlexW3217529431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.