ArticleNature communications2021
Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses.
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Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20citing papers in PubMed
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Who cites it
20 citing papers in PubMed.
- An Update on Anti-COVID-19 Vaccines and the Challenges to Protect Against New SARS-CoV-2 Variants.Pathogens (Basel, Switzerland) · 2025Review
- SARS-CoV-2 Infections in a Triad of Primary School Learners (Grades 1-7), Their Parents, and Teachers in KwaZulu-Natal, South Africa: Protocol for a Cross-Sectional and Nested Case-Cohort Study.JMIR research protocols · 2024Article
- Comparative Immune Response after Vaccination with SOBERANAVaccines · 2023Article
- Tonsils are major sites of persistence of SARS-CoV-2 in children.Microbiology spectrum · 2023Article
- The effect of activity and face masks on exhaled particles in children.Pediatric investigation · 2023Article
- Article
- Classification and severity progression measure of COVID-19 patients using pairs of multi-omic factors.Journal of applied statistics · 2023Article
- Cellular immunity to SARS-CoV-2 following intrafamilial exposure in seronegative family members.Frontiers in immunology · 2023Article
- Policies on children and schools during the SARS-CoV-2 pandemic in Western Europe.Frontiers in public health · 2023Review
- Non-spike and spike-specific memory T cell responses after the third dose of inactivated COVID-19 vaccine.Frontiers in immunology · 2023Article
- Impact of rhinovirus on hospitalization during the COVID-19 pandemic: A prospective cohort study.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022Article
- Spatial clusters, social determinants of health and risk of COVID-19 mortality in Brazilian children and adolescents: A nationwide population-based ecological study.Lancet regional health. Americas · 2022Article
- Promotion of neutralizing antibody-independent immunity to wild-type and SARS-CoV-2 variants of concern using an RBD-Nucleocapsid fusion protein.Nature communications · 2022Article
- SARS-CoV-2 seropositivity and COVID-19 among 5 years-old Amazonian children and their association with poverty and food insecurity.PLoS neglected tropical diseases · 2022Article
- Article
- Article
- SARS-CoV-2 infected children form early immune memory responses dominated by nucleocapsid-specific CD8+ T cells and antibodies.Frontiers in immunology · 2022Article
- T cells in SARS-CoV-2 infection and vaccination.Therapeutic advances in vaccines and immunotherapy · 2022Review
- A Retrospective Outbreak Investigation of a COVID-19 Case Cluster in a Berlin Kindergarten, November 2020.International journal of environmental research and public health · 2021Article
- Rhinovirus as the main co-circulating virus during the COVID-19 pandemic in children.Jornal de pediatriaArticle
Corrections and comments
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Authors and funding
31 authors.
Tiago Fazolo *Departamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0001-6560-7004
Karina Lima *Departamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0003-2478-1182
Julia C Fontoura *Departamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0002-5209-4681
Priscila Oliveira de SouzaDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0002-0445-3897
Gabriel HilarioDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0001-5314-2131
Renata ZorzettoDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0003-3105-1014
Luiz Rodrigues JúniorDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Veridiane Maria PscheidtDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Jayme de Castilhos Ferreira NetoDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Alisson F HaubertDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Izza GambinDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Aline C OliveiraDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Raissa S MelloDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Matheus de Bastos Balbe E GutierresDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil.
Rodrigo Benedetti GassenCenter for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Lais Durço CoimbraBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Sao Paulo, Brazil.
Alexandre BorinBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Sao Paulo, Brazil.ORCID 0000-0003-2935-0752
Rafael Elias MarquesBrazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Sao Paulo, Brazil.ORCID 0000-0002-6949-0947
Ivaine Tais Sauthier SartorSocial Responsibility - PROADI-SUS, Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.
Gabriela Oliveira ZavagliaSocial Responsibility - PROADI-SUS, Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0001-5419-665X
Ingrid Rodrigues FernandesSocial Responsibility - PROADI-SUS, Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0002-0895-0698
Helder I NakayaHospital Israelita Albert Einstein, Jardim Leonor, Sao Paulo, Brazil.ORCID 0000-0001-5297-9108
Fernanda Hammes VarelaSocial Responsibility - PROADI-SUS, Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0003-1947-5279
Márcia Polese-BonattoSocial Responsibility - PROADI-SUS, Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.
Thiago J BorgesCenter for Transplantation Sciences, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Sidia Maria Callegari-JacquesDepartamento de Estatística, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0002-2489-2539
Marcela Santos Correa da CostaCoordenação-Geral do Programa Nacional de Imunizações, Departamento de Imunizações e doenças transmissíveis, Secretaria de vigilância em saúde - Ministério da Saúde (CGPNI/DEIDT/SVS/MS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0002-0636-7941
Jaqueline de Araujo SchwartzCoordenação-Geral do Programa Nacional de Imunizações, Departamento de Imunizações e doenças transmissíveis, Secretaria de vigilância em saúde - Ministério da Saúde (CGPNI/DEIDT/SVS/MS), Porto Alegre, Rio Grande do Sul, Brazil.ORCID 0000-0002-6341-5655
Marcelo Comerlato ScottaSocial Responsibility - PROADI-SUS, Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.
Renato T SteinSocial Responsibility - PROADI-SUS, Hospital Moinhos de Vento, Porto Alegre, Rio Grande do Sul, Brazil.
Cristina BonorinoDepartamento de Ciências Básicas da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brazil. cristinabonorino@gmail.com.ORCID 0000-0003-2755-3978
Funding
No grant is acknowledged in the PubMed record.
Abstract
COVID-19 manifests as a milder disease in children than adults, but the underlying mechanisms are not fully characterized. Here we assess the difference in cellular or humoral immune responses of pediatric and adult COVID-19 patients to see if these factors contribute to the severity dichotomy. Children's non-specific immune profile is dominated by naive lymphocytes and HLA-DR
Indexed as
Immunity, HumoralRNA, ViralAdolescentAdultAgedAntibodies, ViralBrazilCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesChildChild, PreschoolCOVID-19COVID-19 VaccinesCytokinesFemaleHumansAntibodies, ViralCOVID-19 VaccinesCytokinesmRNA VaccinesRNA, MessengerRNA, ViralSpike Glycoprotein, CoronavirusVaccines, SyntheticViral Structural Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.