ArticleNature communications2021
Room-temperature dynamic nuclear polarization enhanced NMR spectroscopy of small biological molecules in water.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Breaking hydrogen bond network enhances oxygenic photosynthesis of photosystem II.Fundamental research · 2026Article
- 14.1 T Liquid-StateJournal of the American Chemical Society · 2026Article
- Single-engineered-residue solvation perturbations regulate global protein architecture and function.Nature communications · 2026Article
- Enhancing NMR Signals in Liquids by Fluorine-19 Overhauser Dynamic Nuclear Polarization (DNP) and Hyperpolarization Transfer to Carbon-13.Angewandte Chemie (International ed. in English) · 2025Article
- Substituted Fullerenes for Enhanced Optical Nuclear Hyperpolarization in Random Orientations.Nature communications · 2025Article
- Distance-Dependence of Photo-CIDNP in Biomimetic Tryptophan-Flavin Diads.Angewandte Chemie (International ed. in English) · 2025Article
- Dynamic nuclear polarization and chemically induced hyperpolarization: Progress, mechanisms, and opportunities.Magnetic resonance letters · 2025Review
- NMR-driven structure-based drug discovery by unveiling molecular interactions.Communications chemistry · 2025Review
- Halogen-Bond-MediatedThe journal of physical chemistry letters · 2025Article
- Overhauser Dynamic Nuclear Polarization Enables Single Scan BenchtopAnalytical chemistry · 2025Article
- Overhauser enhanced liquid state nuclear magnetic resonance spectroscopy in one and two dimensions.Nature communications · 2024Article
- Review
- Triplet dynamic nuclear polarization of pyruvateChemical science · 2023Article
- Polarizing agents beyond pentacene for efficient triplet dynamic nuclear polarization in glass matrices.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- SHARPER-DOSY: Sensitivity enhanced diffusion-ordered NMR spectroscopy.Nature communications · 2023Article
- Spin Hyperpolarization in Modern Magnetic Resonance.Chemical reviews · 2023Review
- Primary Structure of Glycans by NMR Spectroscopy.Chemical reviews · 2023Review
- LargePhysical chemistry chemical physics : PCCP · 2022Article
- NMR methods for the analysis of mixtures.Chemical communications (Cambridge, England) · 2022Review
- Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nuclear magnetic resonance (NMR) spectroscopy is a powerful and popular technique for probing the molecular structures, dynamics and chemical properties. However the conventional NMR spectroscopy is bottlenecked by its low sensitivity. Dynamic nuclear polarization (DNP) boosts NMR sensitivity by orders of magnitude and resolves this limitation. In liquid-state this revolutionizing technique has been restricted to a few specific non-biological model molecules in organic solvents. Here we show that the carbon polarization in small biological molecules, including carbohydrates and amino acids, can be enhanced sizably by in situ Overhauser DNP (ODNP) in water at room temperature and at high magnetic field. An observed connection between ODNP
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