ArticleNature communications2021
Gut microbiome drives individual memory variation in bumblebees.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 71 citations in OpenAlex.
- Gut bacteria prime and reinforce mature leaf oviposition preference in beetles via plant mediated feedback.Nature communications · 2026Article
- A defined community of core gut microbiota members promotes cognitive performance in honey bees.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Conserved gut microbiomes with cross-species spillover between sympatric Neotropical stingless bees and honey bees.Applied and environmental microbiology · 2026Article
- Microbially derived essential amino acids compensate for dietary deficiencies in an ecologically relevant mammalian host.The ISME journal · 2026Article
- Gut microbiota modulates aversive learning and memory of honeybees (Apis mellifera).Nature communications · 2025Article
- Gut microbiota regulates the brain metabolism of sexually mature drones.Microbiology spectrum · 2025Article
- Increasing spatial working memory in mice with Akkermansia muciniphila.Communications biology · 2025Article
- Bumble bee gut microbial community structure differs between species and commercial suppliers, but metabolic potential remains largely consistent.Applied and environmental microbiology · 2025Article
- Probiotic potential ofFrontiers in microbiology · 2025Article
- Colony performance of three native bumblebee species from South China and association with their gut microbiome.Insect science · 2024Article
- The mind, brain, and body study: A protocol for examining the effects of the gut-brain-immune axis on internalizing symptoms in youth exposed to caregiving-related early adversity.Brain, behavior, & immunity - health · 2024Article
- Gut bacteria are essential for development of an invasive bark beetle by regulating glucose transport.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Through an animal's eye: the implications of diverse sensory systems in scientific experimentation.Proceedings. Biological sciences · 2024Review
- Host-microbe interactions: communication in the microbiota-gut-brain axis.Current opinion in microbiology · 2024Review
- The Improving Effects of Probiotic-Added Pollen Substitute Diets on the Gut Microbiota and Individual Health of Honey Bee (Microorganisms · 2024Article
- The honeybee microbiota and its impact on health and disease.Nature reviews. Microbiology · 2024Review
- Gut microbiota contribute to variations in honey bee foraging intensity.The ISME journal · 2024Article
- Antibiotic-altered gut microbiota explain host memory plasticity and disrupt pace-of-life covariation for an aquatic snail.The ISME journal · 2024Article
- Review
- Hive Transplantation Has Minimal Impact on the Core Gut Microbiome of the Australian Stingless Bee, Tetragonula carbonaria.Microbial ecology · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The potential of the gut microbiome as a driver of individual cognitive differences in natural populations of animals remains unexplored. Here, using metagenomic sequencing of individual bumblebee hindguts, we find a positive correlation between the abundance of Lactobacillus Firm-5 cluster and memory retention on a visual discrimination task. Supplementation with the Firm-5 species Lactobacillus apis, but not other non-Firm-5 bacterial species, enhances bees' memory. Untargeted metabolomics after L. apis supplementation show increased LPA (14:0) glycerophospholipid in the haemolymph. Oral administration of the LPA increases long-term memory significantly. Based on our findings and metagenomic/metabolomic analyses, we propose a molecular pathway for this gut-brain interaction. Our results provide insights into proximate and ultimate causes of cognitive differences in natural bumblebee populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.