Evidence map›Paper›PMID 34823641›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2021

Estimated number of deaths directly averted in people 60 years and older as a result of COVID-19 vaccination in the WHO European Region, December 2020 to November 2021.

Margaux Mi Meslé, Jeremy Brown, Piers Mook, José Hagan, Roberta Pastore, Nick Bundle, Gianfranco Spiteri, Giovanni Ravasi, Nathalie Nicolay, Nick Andrews and 18 more

Erratum issuedOpen access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 67 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 2 pooled it
23.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 280 citations in OpenAlex.

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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors at 16 institutions in 14 countries.

Margaux Mi MesléWorld Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark.
Jeremy BrownWorld Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark.
Piers MookWorld Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark.
José HaganWorld Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark.
Roberta PastoreWorld Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark.
Nick BundleEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Gianfranco SpiteriEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Giovanni RavasiEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Nathalie NicolayEuropean Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Nick AndrewsUK Health Security Agency, London, United Kingdom.
Tetiana DykhanovskaPublic Health Center of the MOH of Ukraine (UPHC), Kyiv, Ukraine.
Joël MossongHealth Directorate, Luxembourg, Luxembourg.
Małgorzata Sadkowska-TodysNational Institute of Public Health (NIH) - National Research Institute, Warsaw, Poland.
Raina NikiforovaCentre for Disease Prevention and Control of Latvia, Riga, Latvia.
Flavia RiccardoInstituto Superiore di Sanità, Rome, Italy.
Hinta MeijerinkNorwegian Institute of Public Health, Olso, Norway.
Clara MazagatosInstitute of Health Carlos III, Madrid, Spain.
Jan KynclNational Institute of Public Health, Prague, Czechia.
Jim McMenaminPublic Health Scotland, Glasgow, United Kingdom.
Tanya MelilloMinistry of Public Health, Malta.
Stella KaoustouNational Public Health Organization, Athens, Greece.
Daniel Lévy-BruhlFrench Public Health Agency, Paris, France.
Freek HaarhuisSciensano, Brussels, Belgium.
Rivka RichIsrael Ministry of Health, Jerusalem, Israel.
Meaghan KallUK Health Security Agency, London, United Kingdom.
Dorit NitzanWorld Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark.
Catherine SmallwoodWorld Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark.
Richard G PebodyWorld Health Organization (WHO) Regional Office for Europe, Copenhagen, Denmark.
World Health Organization Regional Office for Europe · DKEuropean Centre for Disease Prevention and Control · SEUK Health Security AgencyInstituto de Salud Carlos III · ESIsrael Ministry of Health · ILIstituto Superiore di Sanità · ITLuxembourg Institute of Health · LUMinistry for Health · MTNational Institute of Public Health · PLNational Institute of Public Health · CZNational Public Health Organization · GRNorwegian Institute of Public Health · NOPublic Health Scotland · GBRiga Technical College · LVSciensano (Belgium) · BEThe State Institution «Public Health Center of the Ministry of Health of Ukraine»

Funding

World Health Organization 001
6 · The paper itself

Abstract

Since December 2019, over 1.5 million SARS-CoV-2-related fatalities have been recorded in the World Health Organization European Region - 90.2% in people ≥ 60 years. We calculated lives saved in this age group by COVID-19 vaccination in 33 countries from December 2020 to November 2021, using weekly reported deaths and vaccination coverage. We estimated that vaccination averted 469,186 deaths (51% of 911,302 expected deaths; sensitivity range: 129,851-733,744; 23-62%). Impact by country ranged 6-93%, largest when implementation was early.

Indexed as

COVID-19COVID-19 VaccinesHumansSARS-CoV-2VaccinationWorld Health OrganizationCOVID-19 VaccinesCOVID-19deaths avertedexpected mortalityolder age groupsvaccination coveragevaccination programs

Identifiers

PMID34823641
PMCPMC8619871
OpenAlexW3216532396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.