Evidence map›Paper›PMID 34823580›Full record

ArticleJournal of medical case reports2021

New Delhi metallo-β-lactamase-1 among Escherichia coli strains isolated from leukemia patients in Iran: two case reports.

Mahdane Roshani, Alireza Goodarzi, Sanaz Dehbashi, Farhad Afrasiabi, Hossein Goudarzi, Ali Hashemi, Mohammad Reza Arabestani

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Mahdane RoshaniDepartment of Microbiology, Faculty of Medicine, Nutrition Research Center, Hamadan University of Medical Sciences, Shahid Fahmideh Street, Park Mardome, Hamadan, IR, Iran.
Alireza GoodarziDepartment of Medical Laboratory Sciences, School of Paramedicine, Hamadan University of Medical Sciences, Shahid Fahmideh Street, Park Mardome, Hamadan, IR, Iran.
Sanaz DehbashiDepartment of Microbiology, Faculty of Medicine, Nutrition Research Center, Hamadan University of Medical Sciences, Shahid Fahmideh Street, Park Mardome, Hamadan, IR, Iran.
Farhad AfrasiabiDepartment of Microbiology, Faculty of Medicine, Nutrition Research Center, Hamadan University of Medical Sciences, Shahid Fahmideh Street, Park Mardome, Hamadan, IR, Iran.
Hossein GoudarziDepartment of Microbiology, Shahid Beheshti University of Medical Sciences, Shahid Shahriari Square, Daneshjou Boulevard, Shahid Chamran Highway, 1983969411, Tehran, Iran.
Ali HashemiDepartment of Microbiology, Shahid Beheshti University of Medical Sciences, Shahid Shahriari Square, Daneshjou Boulevard, Shahid Chamran Highway, 1983969411, Tehran, Iran.
Mohammad Reza ArabestaniDepartment of Microbiology, Faculty of Medicine, Nutrition Research Center, Hamadan University of Medical Sciences, Shahid Fahmideh Street, Park Mardome, Hamadan, IR, Iran. mohammad.arabestani@gmail.com.ORCID http://orcid.org/0000-0001-9991-8193
Hamedan University of Medical Sciences · IRShahid Beheshti University of Medical Sciences · IR

Funding

The Vice Chancellor for Research and Technology, Hamadan University of Medical Sciences 980203554
6 · The paper itself

Abstract

backgroundEscherichia coli has appeared as an important opportunistic pathogen responsible for nosocomial infections in patients with immunodeficiency, particularly in leukemia patients. New Delhi metallo-beta-lactamase is an enzyme originally found in Enterobacteriaceae. CASE PRESENTATION: In this study, 80 isolates of Escherichia coli and Klebsiella pneumoniae were collected over the course of 2 years from two medical centers in Tehran, Iran. Production of carbapenemase was detected in the isolates using modified Hodge test. New Delhi metallo-beta-lactamase-1 genes were detected by polymerase chain reaction amplification with specific primers. Two New Delhi metallo-beta-lactamase-1-producing Escherichia coli strains were isolated from two Iranian patients with leukemia. These two patients were 6 and 15 years old, one female and the other male, from two oncology centers in Iran. The isolates were resistant to carbapenems (imipenem, meropenem), and two isolates were positive for carbapenemase production by modified Hodge test.

conclusionsThe emergence of New Delhi metallo-beta-lactamase-1-producing Escherichia coli is a threat for leukemia patients in oncology and hematology departments. We conclude that the incidence of multidrug resistant pathogens has increased among patients with leukemia and is life threatening.

Indexed as

Escherichia coliLeukemiaAdolescentAnti-Bacterial Agentsbeta-LactamasesChildDrug Resistance, Multiple, BacterialFemaleHumansIranMaleMicrobial Sensitivity TestsAnti-Bacterial Agentsbeta-lactamase NDM-1beta-Lactamasesbla NDM-1Escherichia coliKlebsiella pneumoniaeLeukemia

Identifiers

PMID34823580
PMCPMC8614037
OpenAlexW3216606578

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.