Evidence map›Paper›PMID 34823053›Full record

ReviewSexual medicine2022

ESSM Position Statement on Surgical Treatment of Peyronie's Disease.

Daniar Osmonov, Ahmed Ragheb, Sam Ward, Gideon Blecher, Marco Falcone, Armin Soave, Roland Dahlem, Koenraad van Renterghem, Nim Christopher, Georgios Hatzichristodoulou and 6 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Sexual medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05316714 (Novel Nanofat Regenerative Surgical Technique for Peyronies' Disease Treatment With Penile Lenght Conservation and Non-incisional Albuginea Preservation), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05316714 naunknown statusnot on this map

Novel Nanofat Regenerative Surgical Technique for Peyronies' Disease Treatment With Penile Lenght Conservation and Non-incisional Albuginea Preservation

TypeinterventionalSponsorUniversity of Roma La SapienzaRan2021 to 2022Enrolled35ConditionsPeyronie DiseaseArmsNanofat grafing
3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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  16. Review
  17. [Current treatment concepts for Peyronie's disease].Urologie (Heidelberg, Germany) · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Daniar OsmonovDepartment of Urology and Pediatric Urology, University Hospital Schleswig-Holstein, Kiel, Germany. Electronic address: Daniar.osmonov@uksh.de.
Ahmed RaghebDepartment of Urology, Beni-Suef University, Bedaya Fertility & IVF Hospitals, Kairo, Egypt.
Sam WardDepartment of Urology, Clinique Saint Jean, Brussels; Medicis Medical Center, Woluwe, Belgium.
Gideon BlecherDepartment of Surgery, Monash University, Melbourne; Department of Urology, The Alfred Hospital, Melbourne, Australia.
Marco FalconeDepartment of Urology, University of Turin - Cittàdella Salute e dellaScienza, Turin, Italy.
Armin SoaveDepartment of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Roland DahlemDepartment of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Koenraad van RenterghemDepartment of Urology, Jessa Ziekenhuis Campus Salvator, Hasselt, Belgium.
Nim ChristopherThe Institute of Urology, University College London Hospitals, London, UK.
Georgios HatzichristodoulouDepartment of Urology, Hospital Nürnberg, Nürnberg, Germany.
Mirko PretoDepartment of Urology, University of Turin - Cittàdella Salute e dellaScienza, Turin, Italy.
Giulio GaraffaThe Institute of Urology, University College London Hospitals, London, UK.
Maarten AlbersenDepartment of Urology, UZ Leuven Gasthuisberg Campus, Leuven, Belgium.
Carlo BettocchiDepartment of Urology, University Bari, Bari, Italy.
Giovanni CoronaEndocrinology Unit, Medical Department, AziendaUsl Bologna Maggiore-Bellaria Hospital, Bologna, Italy.
Yacov ReismanFlare-Health, Amstelveen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with Peyronie's disease may experience significat distress. The choice of treatment depends on a variety of factors, including the stage of the disease, the presence of pain, severity and direction of the curvature, penile length and the quality of erectile function.

aimTo review the evidence associated with surgical treatment of Peyronie`s Disease and provide clinical recommendations on behalf of the European Society for Sexual Medicine. 131 peer-reviewed studies and systematic reviews, which were published from 2009 to 2019 in the English language, were included.

methodsMEDLINE, Google Scholar and EMBASE were searched for randomized clinical trials, meta-analyses, open-label prospective and retrospective studies.

main outcome measureThe panel provided statements on clinically relevant questions including patient involvement in the decision process, indications for surgery, choice of the approach, and the management of patient expectations. A comparison of the different grafts used in patients who have undergone plaque incision/excision and grafting in order to identify an ideal graft, has been carried out. The prevalence of postoperative complications has been summarized. Levels of evidence were provided according to the Oxford 2011 criteria and Oxford Centre for Evidence-Based Medicine recommendations.

resultsIn order to allow shared decision making, a patient preoperative counselling regarding the pros and cons of each intervention is recommended. In particular, adverse effects of surgical treatments should be discussed to set realistic understanding and expectations of surgical outcomes and ultimately improve postoperative satisfaction rates. Surgical treatment should be only offered in the chronic phase of the condition, when the deformity and/or degree of erectile dysfunction, prevent patients from engaging in satisfying sexual interaction, or if the deformity is the cause of severe bother.

conclusionsCurrent European Society for Sexual Medicine recommendations cover several aspects of Peyronie's disease treatment. These recommendations aim both to ensure patients and partners have accurate and realistic expectations of their treatment options, as well as to formulate algorithms to guide clinician management pathways. Osmonov D, Ragheb A, Ward S et al, ESSM Position Statement on Surgical Treatment of Peyronie's Disease. Sex Med 2022;10:100459.

Indexed as

Acquired Penile DeviationDisappointmentDissatisfactionInduratio Penis PlasticaPenile GraftPenile LengthPenile ProsthesisPenile ReconstructionPeyronie's DiseasePlication

Identifiers

PMID34823053
PMCPMC8847818

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.