ArticleToxics2021
ChemSkin Reference Chemical Database for the Development of an In Vitro Skin Irritation Test.
Article in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- ChemSkin DB 2.0: a comprehensive reference chemical database for skin corrosion and irritation.Archives of toxicology · 2026Article
- Advances in the application of computational toxicology in cosmetic safety assessment.Archives of toxicology · 2026Review
- Effectiveness of a Natural-Rubber Anal Dilator (ParaSelf) After Pediatric Anorectal Surgery: A Historical-Controlled Intervention Study.Gastroenterology research · 2026Article
- Requirements for Alternative In Vitro and In Silico Skin Models of Irritant and Allergic Contact Dermatitis.Contact dermatitis · 2025Review
- Capacitive Biosensing of Skin Irritants Using a Lanolin-Based Artificial Stratum Corneum Model.Biosensors · 2025Article
- SbD4Skin by EosCloud: Integrating multi-view molecular representation for predicting skin sensitization, irritation, and acute dermal toxicity.Computational and structural biotechnology journal · 2025Article
- Evaluation of a New In Chemico Skin Corrosion Test.Toxicology in vitro : an international journal published in association with BIBRA · 2024Article
- Safety assessment of female sexual hygiene product containing cannabidiol in new zealand white rabbit and clinical trial.Toxicology reports · 2024Article
- Nanophytosomal Gel ofPharmaceuticals (Basel, Switzerland) · 2024Article
- Machine-learning based prediction models for assessing skin irritation and corrosion potential of liquid chemicals using physicochemical properties by XGBoost.Toxicological research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Since the animal test ban on cosmetics in the EU in 2013, alternative in vitro safety tests have been actively researched to replace in vivo animal tests. For the development and evaluation of a new test method, reference chemicals with quality in vivo data are essential to assess the predictive capacity and applicability domain. Here, we compiled a reference chemical database (ChemSkin DB) for the development and evaluation of new in vitro skin irritation tests. The first candidates were selected from 317 chemicals (source data
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.