Evidence map›Paper›PMID 34822678›Full record

ArticleToxics2021

Identification and Characterization of mRNA Biomarkers for Sodium Cyanide Exposure.

Min Kim, Seung-Cheol Jee, Soee Kim, Kyung-Hwa Hwang, Jung-Suk Sung

Abstract read
In one paragraph

Article in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Hazardous waste management and one health approach.Frontiers in public health · 2025
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Physical Activity Rewires the Human Brain against Neurodegeneration.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Min KimDepartment of Life Science, Biomedi Campus, Dongguk University-Seoul, 32 Dongguk-ro, Ilsandong-gu, Goyang 10326, Gyeonggi-do, Korea.ORCID 0000-0001-7287-7002
Seung-Cheol JeeDepartment of Life Science, Biomedi Campus, Dongguk University-Seoul, 32 Dongguk-ro, Ilsandong-gu, Goyang 10326, Gyeonggi-do, Korea.ORCID 0000-0002-9635-9362
Soee KimDepartment of Life Science, Biomedi Campus, Dongguk University-Seoul, 32 Dongguk-ro, Ilsandong-gu, Goyang 10326, Gyeonggi-do, Korea.
Kyung-Hwa HwangJeonbuk Branch, Korea Institute of Toxicology, KIT, KRICT, 30 Baehak 1-gil, Jeongeup-si 56212, Jeollabuk-do, Korea.
Jung-Suk SungDepartment of Life Science, Biomedi Campus, Dongguk University-Seoul, 32 Dongguk-ro, Ilsandong-gu, Goyang 10326, Gyeonggi-do, Korea.ORCID 0000-0002-3145-8458

Funding

Ministry of Environment 2017001970003
6 · The paper itself

Abstract

Biomarkers in exposure assessment are defined as the quantifiable targets that indicate the exposure to hazardous chemicals and their resulting health effect. In this study, we aimed to identify, validate, and characterize the mRNA biomarker that can detect the exposure of sodium cyanide. To identify reliable biomarkers for sodium cyanide exposure, critical criteria were defined for candidate selection: (1) the expression level of mRNA significantly changes in response to sodium thiocyanate treatment in transcriptomics results (fold change > 2.0 or <0.50, adjusted

Indexed as

biomarkerexposure assessmentRNA-seqsodium cyanide

Identifiers

PMID34822678
PMCPMC8624962

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.