Evidence map›Paper›PMID 34822663›Full record

ReviewToxics2021

A Systematic Review of Studies on Genotoxicity and Related Biomarkers in Populations Exposed to Pesticides in Mexico.

Juana Sánchez-Alarcón, Mirta Milić, Vilena Kašuba, María Guadalupe Tenorio-Arvide, José Mariano Rigoberto Montiel-González, Stefano Bonassi, Rafael Valencia-Quintana

Abstract readReview
In one paragraph

Review in Toxics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juana Sánchez-AlarcónLaboratorio "Rafael Villalobos-Pietrini" de Toxicología Genómica y Química Ambiental, Facultad de Agrobiología, Universidad Autónoma de Tlaxcala, CA Genética y Ambiente UATLX-CA 223, Red Temática de Toxicología de Plaguicidas, Tlaxcala 90120, Mexico.ORCID 0000-0002-9105-0251
Mirta MilićMutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.ORCID 0000-0002-9837-7185
Vilena KašubaMutagenesis Unit, Institute for Medical Research and Occupational Health, 10000 Zagreb, Croatia.
María Guadalupe Tenorio-ArvideDepartamento de Investigación en Ciencias Agrícolas, Benemérita Universidad Autónoma de Puebla, Puebla 72570, Mexico.ORCID 0000-0001-6125-4782
José Mariano Rigoberto Montiel-GonzálezLaboratorio "Rafael Villalobos-Pietrini" de Toxicología Genómica y Química Ambiental, Facultad de Agrobiología, Universidad Autónoma de Tlaxcala, CA Genética y Ambiente UATLX-CA 223, Red Temática de Toxicología de Plaguicidas, Tlaxcala 90120, Mexico.
Stefano BonassiDepartment of Human Sciences and Quality of Life Promotion, San Raffaele University, 00166 Rome, Italy.ORCID 0000-0003-3833-6717
Rafael Valencia-QuintanaLaboratorio "Rafael Villalobos-Pietrini" de Toxicología Genómica y Química Ambiental, Facultad de Agrobiología, Universidad Autónoma de Tlaxcala, CA Genética y Ambiente UATLX-CA 223, Red Temática de Toxicología de Plaguicidas, Tlaxcala 90120, Mexico.ORCID 0000-0002-3396-7694

Funding

Consejo Nacional de Ciencia y Tecnología FORDECYT-PRONACES, FOINS 2016-01 3203
6 · The paper itself

Abstract

In agricultural activities, pest control is essential, and the most effective method is the use of chemical agents that also represent an important source of exposure to potentially toxic compounds. Pesticides constitute a heterogeneous group of compounds designed specifically to control different pests. Besides measuring their levels or that of their metabolites in air, plasma, serum, blood, urine, etc., some studies reported increased DNA damage levels after occupational or environmental pesticides exposure, evidenced by several cytogenetic biomarkers such as chromosomal aberrations (CA), sister chromatid exchanges (SCE), micronuclei frequency (MN) together with other nuclear abnormalities (NA), alkaline comet assay, but also changes in oxidative stress parameters and miRNA levels. Single or combined, these techniques have also been used in genotoxic biomonitoring studies of workers occupationally exposed to pesticides in Mexico. Despite being a country with great agricultural activity and reported excessive pesticide use, genotoxic studies have been relatively few and, in some cases, contradictory. A review was made of the studies available (published until the end of 2020 on PubMed, Web of Science, Redalyc and Scielo, both in English and Spanish) in the scientific literature that evaluated occupational exposure of human samples to pesticides assessed with DNA damage and related biomarkers in Mexico.

Indexed as

comet assayDNA damagemicronucleus assaynuclear abnormalitiessisters’ chromatid exchange

Identifiers

PMID34822663
PMCPMC8624200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.