Evidence map›Paper›PMID 34822604›Full record

ArticleToxins2021

Lipid-Binding Aegerolysin from Biocontrol Fungus

Nada Kraševec, Anastasija Panevska, Špela Lemež, Jaka Razinger, Kristina Sepčić, Gregor Anderluh, Marjetka Podobnik

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nada KraševecDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-0925-4272
Anastasija PanevskaDepartment of Biology, Biotechnical Faculty, University of Ljubljana, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-3962-0958
Špela LemežDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Jaka RazingerPlant Protection Department, Agricultural Institute of Slovenia, Hacquetova 17, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-6350-3567
Kristina SepčićDepartment of Biology, Biotechnical Faculty, University of Ljubljana, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-4023-5379
Gregor AnderluhDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-9916-8465
Marjetka PodobnikDepartment of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.ORCID 0000-0001-6786-9737
National Institute of Chemistry · SIUniversity of Ljubljana · SIAgricultural institute of Slovenia · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi are the most common pathogens of insects and thus important regulators of their populations. Lipid-binding aegerolysin proteins, which are commonly found in the fungal kingdom, may be involved in several biologically relevant processes including attack and defense against other organisms. Aegerolysins act alone or together with membrane-attack-complex/perforin (MACPF)-like proteins to form transmembrane pores that lead to cell lysis. We performed an in-depth bioinformatics analysis of aegerolysins in entomopathogenic fungi and selected a candidate aegerolysin, beauveriolysin A (BlyA) from

Indexed as

Pest Control, BiologicalAnimalsBeauveriaComplement Membrane Attack ComplexComputational BiologyFungal ProteinsGenome, FungalHemolysin ProteinsInsectaMembrane LipidsPerforinaegerolysinComplement Membrane Attack ComplexFungal ProteinsHemolysin ProteinsMembrane LipidsPerforinbeauveriolysinbioinformaticsceramide phosphoethanolamine (CPE)entomopathogenic and antagonistic fungilipid bindingmembrane-attack-complex/perforin (MACPF) proteinpore-forming proteins

Identifiers

PMID34822604
PMCPMC8624791
OpenAlexW3217164230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.