Evidence map›Paper›PMID 34822598›Full record

ArticleToxins2021

Individual Variability in

Leijane F Sousa, Matthew L Holding, Tiago H M Del-Rei, Marisa M T Rocha, Rosa H V Mourão, Hipócrates M Chalkidis, Benedito Prezoto, H Lisle Gibbs, Ana M Moura-da-Silva

Open access · goldAbstract readComparative Study
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. BrazilianToxins · 2026
    Article
  2. Acute toxic effects ofToxicon: X · 2026
    Article
  3. Article
  4. Article
  5. Snakebite Envenomations In The Brazilian Amazon: A Little Less Neglected.Revista da Sociedade Brasileira de Medicina Tropical · 2026
    Review
  6. Comparative Hemostatic Effects ofBiochemistry research international · 2026
    Article
  7. Article
  8. Article
  9. Toxins · 2024
    Article
  10. Toxins · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Leijane F SousaLaboratório de Imunopatologia, Instituto Butantan, Av. Vital Brazil, 1500, São Paulo 05503-900, SP, Brazil.ORCID 0000-0001-6303-0897
Matthew L HoldingLife Sciences Institute, University of Michigan, Ann Arbor, MI 48104, USA.ORCID 0000-0003-3477-3012
Tiago H M Del-ReiLaboratório de Imunopatologia, Instituto Butantan, Av. Vital Brazil, 1500, São Paulo 05503-900, SP, Brazil.
Marisa M T RochaLaboratório de Herpetologia, Instituto Butantan, Av. Vital Brazil, 1500, São Paulo 05503-900, SP, Brazil.
Rosa H V MourãoLaboratório de Bioprospecção e Biologia Experimental, Universidade Federal do Oeste do Pará-UFOPA, Rua Vera Paz, s/n, Santarém 68035-110, PA, Brazil.ORCID 0000-0003-0100-644X
Hipócrates M ChalkidisLaboratório de Pesquisas Zoológicas, Unama Centro Universitário da Amazônia, Santarém 68010-200, PA, Brazil.ORCID 0000-0002-7466-9669
Benedito PrezotoLaboratório de Farmacologia, Instituto Butantan, Av. Vital Brazil, 1500, São Paulo 05503-900, SP, Brazil.ORCID 0000-0002-5779-3668
H Lisle GibbsDepartment of Evolution, Ecology, and Organismal Biology, Ohio State University, Columbus, OH 43210-1242, USA.ORCID 0000-0001-7461-3393
Ana M Moura-da-SilvaLaboratório de Imunopatologia, Instituto Butantan, Av. Vital Brazil, 1500, São Paulo 05503-900, SP, Brazil.ORCID 0000-0003-1787-6634
Instituto Butantan · BRThe Ohio State University · USUniversidade da Amazônia · BRUniversidade Federal do Oeste do Pará · BRUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Differences in snake venom composition occur across all taxonomic levels and it has been argued that this variation represents an adaptation that has evolved to facilitate the capture and digestion of prey and evasion of predators.

Indexed as

BothropsAnimalsBrazilCrotalid VenomsEcosystemFemaleMaleProtein IsoformsProteinsCrotalid VenomsProtein IsoformsProteinsBothrops atroxindividual variabilityvenom heterogeneity

Identifiers

PMID34822598
PMCPMC8618853
OpenAlexW3212288754

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.