Evidence map›Paper›PMID 34822594›Full record

ReviewToxins2021

Cosmetic Applications of Bee Venom.

Aida A Abd El-Wahed, Shaden A M Khalifa, Mohamed H Elashal, Syed G Musharraf, Aamer Saeed, Alfi Khatib, Haroon Elrasheid Tahir, Xiaobo Zou, Yahya Al Naggar, Arshad Mehmood and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. The potential of bee products in clinical trials focused on the side effects of radiotherapy and chemotherapy used for cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Natural agents as wound-healing promoters.Inflammopharmacology · 2024
    Review
  13. A Spotlight on the Egyptian Honeybee (Animals : an open access journal from MDPI · 2022
    Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 7 countries.

Aida A Abd El-WahedDepartment of Bee Research, Plant Protection Research Institute, Agricultural Research Centre, Giza 12627, Egypt.ORCID 0000-0002-2200-3507
Shaden A M KhalifaDepartment of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, S-106 91 Stockholm, Sweden.
Mohamed H ElashalDepartment of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt.ORCID 0000-0001-6772-3279
Syed G MusharrafH.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.
Aamer SaeedDepartment of Chemistry, Quaid-i-Azam University, Islamabad 45320, Pakistan.
Alfi KhatibPharmacognosy Research Group, Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Pahang Darul Makmur, Malaysia.ORCID 0000-0002-5480-0789
Haroon Elrasheid TahirSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Xiaobo ZouSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China.
Yahya Al NaggarGeneral Zoology, Institute for Biology, Martin Luther University Halle-Wittenberg, Hoher Weg 8, 06120 Halle, Germany.ORCID 0000-0002-8111-918X
Arshad MehmoodBeijing Engineering and Technology Research Center of Food Additives, Beijing Technology and Business University, Beijing 100048, China.ORCID 0000-0002-2022-375X
Kai WangInstitute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing 100093, China.ORCID 0000-0003-0553-5293
Hesham R El-SeediDepartment of Chemistry, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt.
Jiangsu University · CNAgricultural Research Center · EGAirlangga University · IDBeijing Technology and Business University · CNChinese Academy of Agricultural Sciences · CNMenoufia University · EGQuaid-i-Azam University · PKStockholm University · SETanta University · EGUniversity of Karachi · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bee venom (BV) is a typical toxin secreted by stingers of honeybee workers. BV and BV therapy have long been attractive to different cultures, with extensive studies during recent decades. Nowadays, BV is applied to combat several skin diseases, such as atopic dermatitis, acne vulgaris, alopecia, vitiligo, and psoriasis. BV is used extensively in topical preparations as cosmetics and used as dressing for wound healing, as well as in facemasks. Nevertheless, the safety of BV as a therapeutic choice has always been a concern due to the immune system reaction in some people due to BV use. The documented unfavorable impact is explained by the fact that the skin reactions to BV might expand to excessive immunological responses, including anaphylaxis, that typically resolve over numerous days. This review aims to address bee venom therapeutic uses in skin cosmetics.

Indexed as

Administration, CutaneousAnimalsBeesBee VenomsCosmeticsHumansSkin DiseasesWound HealingBee VenomsCosmeticsbee venomcosmetics applicationsskin diseases

Identifiers

PMID34822594
PMCPMC8625659
OpenAlexW3212409662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.