Evidence map›Paper›PMID 34822589›Full record

ArticleToxins2021

In Vitro and In Vivo Toxicity Evaluation of Natural Products with Potential Applications as Biopesticides.

Felicia Sangermano, Marco Masi, Amrish Kumar, Ravindra Peravali, Angela Tuzi, Alessio Cimmino, Daniela Vallone, Giuliana Giamundo, Ivan Conte, Antonio Evidente and 1 more

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Felicia SangermanoDepartment of Biology, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Naples, Italy.
Marco MasiDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0003-0609-8902
Amrish KumarInstitute for Biological and Chemical Systems-Biological Information Processing (IBCS-BIP), Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.
Ravindra PeravaliInstitute for Biological and Chemical Systems-Biological Information Processing (IBCS-BIP), Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.
Angela TuziDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Naples, Italy.
Alessio CimminoDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0002-1551-4237
Daniela ValloneInstitute for Biological and Chemical Systems-Biological Information Processing (IBCS-BIP), Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany.
Giuliana GiamundoTelethon Institute of Genetics and Medicine, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0002-3101-4697
Ivan ConteDepartment of Biology, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0002-8968-9021
Antonio EvidenteDepartment of Chemical Sciences, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0001-9110-1656
Viola CalabròDepartment of Biology, University of Naples Federico II, Complesso Universitario Monte Sant'Angelo, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0002-6508-8889
University of Naples Federico II · ITKarlsruhe Institute of Technology · DETelethon Institute Of Genetics And Medicine · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of natural products in agriculture as pesticides has been strongly advocated. However, it is necessary to assess their toxicity to ensure their safe use. In the present study, mammalian cell lines and fish models of the zebrafish (

Indexed as

AnimalsBiological Control AgentsBiological ProductsCell LineEmbryo, NonmammalianHumansMiceOryziasToxicity TestsZebrafishBiological Control AgentsBiological Productsagricultural applicationcyclopaldic and α-costic acidscytotoxicitydevelopmental toxicityDNA damagefish embryosplant and microbial metabolites

Identifiers

PMID34822589
PMCPMC8617648
OpenAlexW3212187418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.