Evidence map›Paper›PMID 34822584›Full record

ArticleToxins2021

Evaluation of Protection by Caffeic Acid, Chlorogenic Acid, Quercetin and Tannic Acid against the In Vitro Neurotoxicity and In Vivo Lethality of

Isadora Caruso Fontana Oliveira, Edson Hideaki Yoshida, Murilo Melo Juste Dini, Ana Beatriz Olívio Paschoal, José Carlos Cogo, Maria Alice da Cruz-Höfling, Stephen Hyslop, Yoko Oshima-Franco

Open access · goldAbstract readComparative Study
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Pharmaceuticals (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Isadora Caruso Fontana OliveiraPost-Graduate Program in Pharmaceutical Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares km 92.5, Sorocaba 18023-000, SP, Brazil.
Edson Hideaki YoshidaPost-Graduate Program in Pharmaceutical Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares km 92.5, Sorocaba 18023-000, SP, Brazil.
Murilo Melo Juste DiniPost-Graduate Program in Pharmaceutical Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares km 92.5, Sorocaba 18023-000, SP, Brazil.
Ana Beatriz Olívio PaschoalPost-Graduate Program in Pharmaceutical Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares km 92.5, Sorocaba 18023-000, SP, Brazil.
José Carlos CogoBioengineering and Biomedical Engineering Programs, Technological and Scientific Institute, Brazil University, Rua Carolina Fonseca, 584/235, São Paulo 08230-030, SP, Brazil.
Maria Alice da Cruz-HöflingDepartment of Structural and Functional Biology, Institute of Biology, State University of Campinas (UNICAMP), Rua Monteiro Lobato, 255, Cidade Universitária Zeferino Vaz, Campinas 13083-862, SP, Brazil.
Stephen HyslopDepartment of Translational Medicine (Section of Pharmacology), Faculty of Medical Sciences, State University of Campinas (UNICAMP), Rua Tessália Vieira de Camargo, 126, Campinas 13083-970, SP, Brazil.
Yoko Oshima-FrancoPost-Graduate Program in Pharmaceutical Sciences, University of Sorocaba (UNISO), Rodovia Raposo Tavares km 92.5, Sorocaba 18023-000, SP, Brazil.
Universidade de Sorocaba · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Brasil · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic envenomation by

Indexed as

AnimalsAntiveninsCaffeic AcidsChlorogenic AcidCrotalid VenomsCrotalusElectrophoresis, Polyacrylamide GelFemaleMaleMiceNeurotoxicity SyndromesPhrenic NerveQuercetinRatsRats, WistarTanninsAntiveninscaffeic acidCaffeic AcidsChlorogenic AcidCrotalid VenomsQuercetinTanninsantivenomphytochemicalrattlesnake venomtannic acid

Identifiers

PMID34822584
PMCPMC8623703
OpenAlexW3212487700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.