Evidence map›Paper›PMID 34822578›Full record

ArticleToxins2021

Assessment of Dietary Exposure to Ochratoxin A in Lebanese Students and Its Urinary Biomarker Analysis.

Manar Al Ayoubi, Mohammad Salman, Lucia Gambacorta, Nada El Darra, Michele Solfrizzo

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Manar Al AyoubiDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, Tarik El Jedidah-Beirut, P.O. Box 115020 Riad EL Solh, Beirut 1107 2809, Lebanon.ORCID 0000-0001-5733-9986
Mohammad SalmanMycotoxins Department, Lebanese Agricultural Research Institute, Fanar P.O. Box 2611, Beirut 1107 2809, Lebanon.
Lucia GambacortaInstitute of Sciences of Food Production (ISPA), National Research Council of Italy, V. Amendola 122/o, 70126 Bari, Italy.
Nada El DarraDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Beirut Arab University, Tarik El Jedidah-Beirut, P.O. Box 115020 Riad EL Solh, Beirut 1107 2809, Lebanon.ORCID 0000-0002-6568-5536
Michele SolfrizzoInstitute of Sciences of Food Production (ISPA), National Research Council of Italy, V. Amendola 122/o, 70126 Bari, Italy.
Beirut Arab University · LBInstitute of Sciences of Food Production · ITLebanese Agricultural Research Institute · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study investigated the dietary and urinary OTA occurrence among 44 Lebanese children. Relying on HPLC-FLD analysis, OTA was found in all the urine samples and in 46.5% and 25% of the 24 h duplicate diet and dinner samples, respectively. The means of OTA levels in positive samples were 0.32 ± 0.1 ng/g in 24 h diet, 0.32 ± 0.18 ng/g in dinner and 0.022 ± 0.012 ng/mL in urines. These values corresponded to margin of exposure (MOE) means of 7907 ± 5922 (neoplastic) and 2579 ± 1932 (non-neoplastic) calculated from positive 24 h diet, while 961 ± 599 (neoplastic) and 313 ± 195 (non-neoplastic) calculated from the urine. Since the MOE levels for the neoplastic effect were below the limit (10,000), a major health threat was detected and must be addressed as a health institutions' priority. Besides, the wide difference between PDIs and MOEs calculated from food and urine suggests conducting further OTA's toxicokinetics studies before using urine to measure OTA exposure.

Indexed as

AdolescentBiomarkersDietary ExposureFemaleFood ContaminationHumansLebanonMaleOchratoxinsUrinalysisBiomarkersochratoxin AOchratoxinsbiomarkerduplicate dietsexposureOchratoxin Arisk assessmenturine

Identifiers

PMID34822578
PMCPMC8617721
OpenAlexW3211684826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.