Evidence map›Paper›PMID 34822517›Full record

ArticleMarine drugs2021

Complete Lipooligosaccharide Structure from

Rossella Di Guida, Angela Casillo, Antonietta Stellavato, Celeste Di Meo, Soichiro Kawai, Jun Kawamoto, Takuya Ogawa, Tatsuo Kurihara, Chiara Schiraldi, Maria Michela Corsaro

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Optimization of growth ofFrontiers in bioengineering and biotechnology · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Rossella Di GuidaDepartment of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0002-8167-5338
Angela CasilloDepartment of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy.
Antonietta StellavatoDepartment of Experimental Medicine, Section of Biotechnology Medical Histology and Molecular Biology, University of Campania "Luigi Vanvitelli", Via L. De Crecchio n 7, 80138 Naples, Italy.ORCID 0000-0003-1635-2724
Celeste Di MeoDepartment of Experimental Medicine, Section of Biotechnology Medical Histology and Molecular Biology, University of Campania "Luigi Vanvitelli", Via L. De Crecchio n 7, 80138 Naples, Italy.
Soichiro KawaiInstitute for Chemical Research, Kyoto University, Kyoto 611-0011, Japan.
Jun KawamotoInstitute for Chemical Research, Kyoto University, Kyoto 611-0011, Japan.ORCID 0000-0002-5025-5613
Takuya OgawaInstitute for Chemical Research, Kyoto University, Kyoto 611-0011, Japan.
Tatsuo KuriharaInstitute for Chemical Research, Kyoto University, Kyoto 611-0011, Japan.ORCID 0000-0002-7777-1378
Chiara SchiraldiDepartment of Experimental Medicine, Section of Biotechnology Medical Histology and Molecular Biology, University of Campania "Luigi Vanvitelli", Via L. De Crecchio n 7, 80138 Naples, Italy.ORCID 0000-0002-1066-843X
Maria Michela CorsaroDepartment of Chemical Sciences, University of Naples "Federico II", Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy.ORCID 0000-0002-6834-8682
Kyoto University · JPUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipopolysaccharides (LPS) are surface glycoconjugates embedded in the external leaflet of the outer membrane (OM) of the Gram-negative bacteria. They consist of three regions: lipid A, core oligosaccharide (OS), and O-specific polysaccharide or O-antigen. Lipid A is the glycolipid endotoxin domain that anchors the LPS molecule to the OM, and therefore, its chemical structure is crucial in the maintenance of membrane integrity in the Gram-negative bacteria. In this paper, we reported the characterization of the lipid A and OS structures from

Indexed as

FishesPseudoalteromonasAnimalsAquatic OrganismsCaco-2 CellsHumansImmunologic FactorsLipopolysaccharidesNF-kappa BStructure-Activity RelationshipImmunologic FactorsLipopolysaccharidesNF-kappa Bcold-adaptedendotoxinfish-gut bacteriumlipid ALPSmass spectrometryNMRstructural characterizationTLR-4

Identifiers

PMID34822517
PMCPMC8623723
OpenAlexW3211830198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.