Evidence map›Paper›PMID 34822514›Full record

ArticleMarine drugs2021

Formulation, Optimization and In Vivo Evaluation of Fucoidan-Based Cream with Anti-Inflammatory Properties.

Ekaterina D Obluchinskaya, Olga N Pozharitskaya, Elena V Flisyuk, Alexander N Shikov

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  12. From Ocean to Medicine: Harnessing Seaweed's Potential for Drug Development.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Fucoidan fromMarine drugs · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ekaterina D ObluchinskayaMurmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), Vladimirskaya, 17, Murmansk 183010, Russia.ORCID 0000-0003-4456-656X
Olga N PozharitskayaMurmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), Vladimirskaya, 17, Murmansk 183010, Russia.ORCID 0000-0003-1061-0665
Elena V FlisyukDepartment of Technology of Pharmaceutical Formulations, St. Petersburg State Chemical Pharmaceutical University, Prof. Popov, 14a, Saint-Petersburg 197376, Russia.
Alexander N ShikovMurmansk Marine Biological Institute of the Russian Academy of Sciences (MMBI RAS), Vladimirskaya, 17, Murmansk 183010, Russia.ORCID 0000-0003-4351-0695
Murmansk Marine Biological Institute · RUSaint - Petersburg State Chemical Pharmaceutical Academy · RU

Funding

Government Assignment to the Murmansk Marine Biological Institute Russian Academy of Sci-ences (Russia) (basic funding) Government Assignment
6 · The paper itself

Abstract

Fucoidan is a polysaccharide found in brown alga with glorious potential for pharmacological activities, among which its anti-inflammatory properties have gained meaningful attention. Due to several advantages of formulations for topical application, this study aimed to develop and optimize a fucoidan-based cream formulation and to investigate its anti-inflammatory potential after topical application in vivo. Fucoidan from

Indexed as

PhaeophyceaeAdministration, CutaneousAnimalsAnti-Inflammatory AgentsAquatic OrganismsCarrageenanDisease Models, AnimalDose-Response Relationship, DrugDrug CompoundingEdemaFemalePolysaccharidesRatsRats, WistarAnti-Inflammatory AgentsCarrageenanfucoidanPolysaccharidesanti-inflammatorycreamdrug releaseformulation developmentfucoidantopical application

Identifiers

PMID34822514
PMCPMC8620601
OpenAlexW3213609052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.