Evidence map›Paper›PMID 34822503›Full record

ArticleMarine drugs2021

Unravelling the Anti-Inflammatory and Antioxidant Potential of the Marine Sponge

Joana Alves, Helena Gaspar, Joana Silva, Celso Alves, Alice Martins, Fernando Teodoro, Patrícia Susano, Susete Pinteus, Rui Pedrosa

Abstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Joana AlvesMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0003-0524-9270
Helena GasparMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0002-1613-7023
Joana SilvaMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0003-1224-1699
Celso AlvesMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0003-1581-2127
Alice MartinsMARE-Marine and Environmental Sciences Centre, Escola Superior de Turismo e Tecnologia do Mar, Politécnico de Leiria, 2520-614 Peniche, Portugal.
Fernando TeodoroMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0001-5384-1469
Patrícia SusanoMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.
Susete PinteusMARE-Marine and Environmental Sciences Centre, Politécnico de Leiria, 2520-630 Peniche, Portugal.ORCID 0000-0002-3290-3111
Rui PedrosaMARE-Marine and Environmental Sciences Centre, Escola Superior de Turismo e Tecnologia do Mar, Politécnico de Leiria, 2520-614 Peniche, Portugal.

Funding

Fundação para a Ciência e Tecnologia (SAICTPAC/0019/ 2015-LISBOA- 01-0145-FEDER-016405Fundação para a Ciência e Tecnologia SFRH/BD/103255/2014Fundação para a Ciência e Tecnologia UIDB/04046/2020Fundação para a Ciência e Tecnologia UIDB/04292/2020Fundação para a Ciência e Tecnologia UIDP/04292/2020Fundação para a Ciência e Tecnologia and COMPETE PTDC/BIA-OUT/29250/2017; POCI-01-0145-FEDER-029250
6 · The paper itself

Abstract

Inflammation is a double-edged sword, as it can have both protective effects and harmful consequences, which, combined with oxidative stress (OS), can lead to the development of deathly chronic inflammatory conditions. Over the years, research has evidenced the potential of marine sponges as a source of effective anti-inflammatory therapeutic agents. Within this framework, the purpose of this study was to evaluate the antioxidant and the anti-inflammatory potential of the marine sponge

Indexed as

PoriferaAnimalsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsAquatic OrganismsCell Line, TumorHT29 CellsHumansLipopolysaccharidesMicePortugalRAW 264.7 CellsAnti-Inflammatory AgentsAntineoplastic AgentsAntioxidantsLipopolysaccharideschronic diseasesinflammationmarine natural productsmarine spongesoxidative stressRAW 264.7.6

Identifiers

PMID34822503
PMCPMC8625174

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.