Evidence map›Paper›PMID 34822480›Full record

ArticleMarine drugs2021

Cytoprotective Peptides from Blue Mussel Protein Hydrolysates: Identification and Mechanism Investigation in Human Umbilical Vein Endothelial Cells Injury.

Indyaswan Tegar Suryaningtyas, Chang-Bum Ahn, Jae-Young Je

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Brown AlgaeMarine drugs · 2024
    Article
  4. Bioactive Peptides fromNutrients · 2024
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Indyaswan Tegar SuryaningtyasDepartment of Food and Life Science, Pukyong National University, Busan 48513, Korea.
Chang-Bum AhnDivision of Food and Nutrition, Chonnam National University, Gwangju 61186, Korea.
Jae-Young JeDepartment of Marine-Bio Convergence Science, Pukyong National University, Busan 48547, Korea.ORCID 0000-0002-4800-0566
Pukyong National University · KRChonnam National University · KR

Funding

the National Research Foundation of Korea (NRF) 2021R1I1A3047702
6 · The paper itself

Abstract

Cardiovascular disease represents a leading cause of mortality and is often characterized by the emergence of endothelial dysfunction (ED), a physiologic condition that takes place in the early progress of atherosclerosis. In this study, two cytoprotective peptides derived from blue mussel chymotrypsin hydrolysates with the sequence of EPTF and FTVN were purified and identified. Molecular mechanisms underlying the cytoprotective effects against oxidative stress which lead to human umbilical vein endothelial cells (HUVEC) injury were investigated. The results showed that pretreatment of EPTF, FTVN and their combination (1:1) in 0.1 mg/mL significantly reduced HUVEC death due to H

Indexed as

BivalviaAnimalsApoptosisCoronary Artery DiseaseHumansHuman Umbilical Vein Endothelial CellsHydrogen PeroxideProtective AgentsProtein HydrolysatesHydrogen PeroxideProtective AgentsProtein Hydrolysatesbioactive peptideblue musselcytoprotectiveendothelial dysfunctionoxidative stress

Identifiers

PMID34822480
PMCPMC8620150
OpenAlexW3208145360

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.