ArticleMetabolites2021
A Core Metabolome Response of Maize Leaves Subjected to Long-Duration Abiotic Stresses.
Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Abiotic Stress in Crop Production.International journal of molecular sciences · 2023Pooled it
- γ-Aminobutyric Acid (GABA) enhances heat tolerance in rice via integrated antioxidant defense, metabolic homeostasis and heat shock response.BMC plant biology · 2026Article
- Responses and adaptations of plants to abiotic stress: transcriptional regulation of secondary metabolic pathways, metabolomics, and nanobiological approaches.Frontiers in genetics · 2026Review
- The Effect of Exogenously Applied Dicarboxylic Acids (Photon) on the Maize (Zea mays) Metabolite Profile.Chemistry & biodiversity · 2025Article
- Progress in Transcriptomics and Metabolomics in Plant Responses to Abiotic Stresses.Current issues in molecular biology · 2025Review
- Impact of High-Temperature Stress on Maize Seed Setting: Cellular and Molecular Insights of Thermotolerance.International journal of molecular sciences · 2025Review
- Maize and heat stress: Physiological, genetic, and molecular insights.The plant genome · 2024Review
- Identification and Alternative Splicing Profile of theInternational journal of molecular sciences · 2023Article
- Responses of Aroma Related Metabolic Attributes ofPlants (Basel, Switzerland) · 2023Article
- Global Responses of Autopolyploid Sugarcane Badila (International journal of molecular sciences · 2023Article
- Raffinose degradation-related geneFrontiers in plant science · 2023Article
- The Plant Metabolic Changes and the Physiological and Signaling Functions in the Responses to Abiotic Stress.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Nutritional, functional, and bioactive properties of african underutilized legumes.Frontiers in plant science · 2023Review
- Identification, Characterization and Expression Profiling of the RS Gene Family during the Withering Process of White Tea in the Tea Plant (International journal of molecular sciences · 2022Article
- Grape Berry Responses to Sequential Flooding and Heatwave Events: A Physiological, Transcriptional, and Metabolic Overview.Plants (Basel, Switzerland) · 2022Article
- Metabolome Profiling: A Breeding Prediction Tool for Legume Performance under Biotic Stress Conditions.Plants (Basel, Switzerland) · 2022Review
- Reprogramming of Plant Central Metabolism in Response to Abiotic Stresses: A Metabolomics View.International journal of molecular sciences · 2022Review
- Heat Stress-Mediated Constraints in Maize (Frontiers in plant science · 2022Review
- Soil Moisture and Its Interaction With Temperature Determine Root Metabolomes of a Himalayan Alpine Shrub.Physiologia plantarumArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
Abiotic stresses reduce crop growth and yield in part by disrupting metabolic homeostasis and triggering responses that change the metabolome. Experiments designed to understand the mechanisms underlying these metabolomic responses have usually not used agriculturally relevant stress regimes. We therefore subjected maize plants to drought, salt, or heat stresses that mimic field conditions and analyzed leaf responses at metabolome and transcriptome levels. Shared features of stress metabolomes included synthesis of raffinose, a compatible solute implicated in tolerance to dehydration. In addition, a marked accumulation of amino acids including proline, arginine, and γ-aminobutyrate combined with depletion of key glycolysis and tricarboxylic acid cycle intermediates indicated a shift in balance of carbon and nitrogen metabolism in stressed leaves. Involvement of the γ-aminobutyrate shunt in this process is consistent with its previously proposed role as a workaround for stress-induced thiamin-deficiency. Although convergent metabolome shifts were correlated with gene expression changes in affected pathways, patterns of differential gene regulation induced by the three stresses indicated distinct signaling mechanisms highlighting the plasticity of plant metabolic responses to abiotic stress.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.