Evidence map›Paper›PMID 34822438›Full record

ReviewMetabolites2021

Recent Advances of Ambient Mass Spectrometry Imaging and Its Applications in Lipid and Metabolite Analysis.

Keke Qi, Liutian Wu, Chengyuan Liu, Yang Pan

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  11. Recent Analytical Methodologies in Lipid Analysis.International journal of molecular sciences · 2024
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Keke QiNational Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China.ORCID 0000-0002-3993-4033
Liutian WuNational Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China.
Chengyuan LiuNational Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China.ORCID 0000-0002-8690-8698
Yang PanNational Synchrotron Radiation Laboratory, University of Science and Technology of China, Hefei 230029, China.

Funding

the National Key Research and D evelopment Program of China 2016YFA0400903the National Natural Science Foundation of China 1210050090
6 · The paper itself

Abstract

Ambient mass spectrometry imaging (AMSI) has attracted much attention in recent years. As a kind of unlabeled molecular imaging technique, AMSI can enable in situ visualization of a large number of compounds in biological tissue sections in ambient conditions. In this review, the developments of various AMSI techniques are discussed according to one-step and two-step ionization strategies. In addition, recent applications of AMSI for lipid and metabolite analysis (from 2016 to 2021) in disease diagnosis, animal model research, plant science, drug metabolism and toxicology research, etc., are summarized. Finally, further perspectives of AMSI in spatial resolution, sensitivity, quantitative ability, convenience and software development are proposed.

Indexed as

ambient mass spectrometry imaging (AMSI)lipidmetabolite

Identifiers

PMID34822438
PMCPMC8625079

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.