Evidence map›Paper›PMID 34822413›Full record

ArticleMetabolites2021

Glutamine Homeostasis and Its Role in the Adaptive Strategies of the Blind Mole Rat, Spalax.

Dmitry Miskevich, Anastasia Chaban, Maria Dronina, Ifat Abramovich, Eyal Gottlieb, Imad Shams

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Research Progress in Skin Aging, Metabolism, and Related Products.International journal of molecular sciences · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Dmitry MiskevichDepartment of Evolutionary and Environmental Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3498838, Israel.ORCID 0000-0001-9563-509X
Anastasia ChabanDepartment of Evolutionary and Environmental Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3498838, Israel.
Maria DroninaInstitute of Evolution, University of Haifa, Haifa 3498838, Israel.
Ifat AbramovichTechnion Faculty of Medicine, Haifa 3525433, Israel.
Eyal GottliebTechnion Faculty of Medicine, Haifa 3525433, Israel.
Imad ShamsDepartment of Evolutionary and Environmental Biology, Faculty of Natural Sciences, University of Haifa, Haifa 3498838, Israel.ORCID 0000-0001-6496-2928
University of Haifa · ILTechnion – Israel Institute of Technology · IL

Funding

Israel Science Foundation 1935/17John Templeton Foundation 53057Kadas Family Charitable Foundation 000
6 · The paper itself

Abstract

Oxidative metabolism is fine-tuned machinery that combines two tightly coupled fluxes of glucose and glutamine-derived carbons. Hypoxia interrupts the coordination between the metabolism of these two nutrients and leads to a decrease of the system efficacy and may eventually cause cell death. The subterranean blind mole rat,

Indexed as

adaptationbioenergeticsglutamineGSHhypoxiametabolomeproline cycle

Identifiers

PMID34822413
PMCPMC8620300
OpenAlexW3211029772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.