Evidence map›Paper›PMID 34822401›Full record

ArticleMetabolites2021

MetaFetcheR: An R Package for Complete Mapping of Small-Compound Data.

Sara A Yones, Rajmund Csombordi, Jan Komorowski, Klev Diamanti

Abstract read
In one paragraph

Article in Metabolites, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Metabolite names and identifiers: how far are we from interoperability?Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sara A YonesDepartment of Cellular and Molecular Biology, Uppsala University, 751 24 Uppsala, Sweden.ORCID 0000-0002-7201-2604
Rajmund CsombordiDepartment of Cellular and Molecular Biology, Uppsala University, 751 24 Uppsala, Sweden.
Jan KomorowskiDepartment of Cellular and Molecular Biology, Uppsala University, 751 24 Uppsala, Sweden.
Klev DiamantiDepartment of Cellular and Molecular Biology, Uppsala University, 751 24 Uppsala, Sweden.ORCID 0000-0002-4922-8415

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Small-compound databases contain a large amount of information for metabolites and metabolic pathways. However, the plethora of such databases and the redundancy of their information lead to major issues with analysis and standardization. A lack of preventive establishment of means of data access at the infant stages of a project might lead to mislabelled compounds, reduced statistical power, and large delays in delivery of results. We developed MetaFetcheR, an open-source R package that links metabolite data from several small-compound databases, resolves inconsistencies, and covers a variety of use-cases of data fetching. We showed that the performance of MetaFetcheR was superior to existing approaches and databases by benchmarking the performance of the algorithm in three independent case studies based on two published datasets.

Indexed as

metabolitesmetabolomicsqueue-based algorithmsmall-compound databases

Identifiers

PMID34822401
PMCPMC8620779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.