Evidence map›Paper›PMID 34822215›Full record

SynthesisJournal of thrombosis and haemostasis : JTH2022

An update on the global use of risk assessment models and thromboprophylaxis in hospitalized patients with medical illnesses from the World Thrombosis Day steering committee: Systematic review and meta-analysis.

Gabor Forgo, Evy Micieli, Walter Ageno, Lana A Castellucci, Gabriela Cesarman-Maus, Henry Ddungu, Erich Vinicius De Paula, Mert Dumantepe, Maria Cecilia Guillermo Esposito, Stavros V Konstantinides and 7 more

Open access · hybridAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of thrombosis and haemostasis : JTH, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  11. Review
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  16. Overuse and underuse of thromboprophylaxis in medical inpatients.Research and practice in thrombosis and haemostasis · 2023
    Article
  17. Article
  18. Article
  19. Observational
  20. A systematic approach to venous thromboembolism prevention: a focus on UK experience.Research and practice in thrombosis and haemostasis · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 13 institutions in 13 countries.

Gabor ForgoDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0003-0810-750X
Evy MicieliDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0001-6896-9924
Walter AgenoDepartment of Clinical Medicine, University of Insubria, Varese, Italy.
Lana A CastellucciDepartment of Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.
Gabriela Cesarman-MausDepartment of Hematology, Instituto Nacional de Cancerología, Mexico City, Mexico.ORCID 0000-0002-8397-0330
Henry DdunguUganda Cancer Institute, Kampala, Uganda.
Erich Vinicius De PaulaSchool of Medical Sciences and Division of Hematology, University of Campinas, Campinas, Brazil.ORCID 0000-0003-1539-7912
Mert DumantepeDepartment of Cardiovascular Surgery, Uskudar University School of Medicine, Istanbul, Turkey.
Maria Cecilia Guillermo EspositoDepartment of Hematology, Hospital de Clinicas Facultad de Medicina, Universidad de la República Montevideo, Montevideo, Uruguay.
Stavros V KonstantinidesCenter for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.ORCID 0000-0001-6359-7279
Nils KucherDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.
Claire McLintockNational Women's Health Auckland City Hospital Auckland New Zealand, Auckland, New Zealand.ORCID 0000-0002-4771-8760
Fionnuala Ní ÁinleDepartment of Haematology, Mater Misericordiae University Hospital and Rotunda Hospital, Dublin, Ireland.ORCID 0000-0003-0163-792X
Alex C SpyropoulosInstitute for Health Innovations and Outcomes Research, Feinstein Institutes for Medical Research and the Zucker School of Medicine at Hofstra/Northwell, New York, New York, USA.ORCID 0000-0002-3175-461X
Tetsumei UranoShizuoka Graduate University of Public Health, Shizuoka, Japan.
Beverley J HuntThrombosis & Haemophilia Centre, Guys & St Thomas' NHS Foundation Trust, London, UK.ORCID 0000-0002-4709-0774
Stefano BarcoDepartment of Angiology, University Hospital Zurich, Zurich, Switzerland.ORCID 0000-0002-2618-347X
University Hospital of Zurich · CHJohannes Gutenberg University Mainz · DEAuckland City Hospital · NZGuy's and St Thomas' NHS Foundation Trust · GBInstituto Nacional de Cancerología · MXNorthwell Health · USUganda Cancer Institute · UGUniversidad de la República de Uruguay · UYUniversidade Estadual de Campinas (UNICAMP) · BRUniversity College Dublin · IEUniversity of Insubria · ITUniversity of Ottawa · CAÜsküdar University · TR

Funding

Expanding independent research capacity in HIV-associated malignancies in UgandaD43TW009759 · FIC · FRED HUTCHINSON CANCER RESEARCH CENTER · PI OREM, JACKSON, PHIPPS, WARREN · 2014 to 2023
$3.0M
6 · The paper itself

Abstract

introductionVenous thromboembolism (VTE) is a leading cause of cardiovascular morbidity and mortality. The majority of VTE events are hospital-associated. In 2008, the Epidemiologic International Day for the Evaluation of Patients at Risk for Venous Thromboembolism in the Acute Hospital Care Setting (ENDORSE) multinational cross-sectional study reported that only approximately 40% of medical patients at risk of VTE received adequate thromboprophylaxis.

methodsIn our systematic review and meta-analysis, we aimed at providing updated figures concerning the use of thromboprophylaxis globally. We focused on: (a) the frequency of patients with an indication to thromboprophylaxis according with individual models; (b) the use of adequate thromboprophylaxis; and (c) reported contraindications to thromboprophylaxis. Observational nonrandomized studies or surveys focusing on medically ill patients were considered eligible.

resultsAfter screening, we included 27 studies from 20 countries for a total of 137 288 patients. Overall, 50.5% (95% confidence interval [CI]: 41.9-59.1, I

conclusionsThe use of anticoagulants for VTE prevention has been proven effective and safe, but thromboprophylaxis prescriptions are still unsatisfactory among hospitalized medically ill patients around the globe with marked geographical differences.

Indexed as

ThrombosisVenous ThromboembolismAnticoagulantsCross-Sectional StudiesHumansRisk AssessmentRisk FactorsAnticoagulantsepidemiologythromboprophylaxisthrombosisvenous thromboembolismWorld Thrombosis Day

Identifiers

PMID34822215
PMCPMC9299991
OpenAlexW3216054869

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.