Evidence map›Paper›PMID 34822139›Full record

ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2022

Relationship Between Cardiorespiratory Fitness, Baseline Blood Pressure and Hypertensive Response to Exercise in the Ferrari Corporate Population.

Alessandro Biffi, Giovanna Gallo, Fredrick Fernando, Felice Sirico, Maria Grazia Signorello, Lorena De Martino, George Emil Manole, Stefano Palermi, Massimo Volpe

Abstract read
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In one paragraph

Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Distribution of Cardiovascular Modifiable Risk Factors in a Corporate Wellness Program: A Case Study of Occupational Cardiology in the Ferrari Company.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Editorial: Cardiovascular disease prevention in the workplace.Frontiers in cardiovascular medicine · 2024
    Article
  8. Review
  9. Association of CYP2C19 Polymorphic Markers with Cardiovascular Disease Risk Factors in Gas Industry Workers Undergoing Periodic Medical Examinations.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2023
    Article
  10. Review
  11. Article
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  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alessandro Biffi *Med-Ex, Medicine and Exercise srl, Medical Partner Scuderia Ferrari, Rome, Italy.
Giovanna Gallo *Cardiology Unit, Department of Clinical and Molecular Medicine, School of Medicine and Psychology, Sapienza University of Rome, Rome, Italy. giovanna.gallo@uniroma1.it.ORCID http://orcid.org/0000-0003-4845-117X
Fredrick FernandoMed-Ex, Medicine and Exercise srl, Medical Partner Scuderia Ferrari, Rome, Italy.
Felice SiricoMed-Ex, Medicine and Exercise srl, Medical Partner Scuderia Ferrari, Rome, Italy.
Maria Grazia SignorelloMed-Ex, Medicine and Exercise srl, Medical Partner Scuderia Ferrari, Rome, Italy.
Lorena De MartinoMed-Ex, Medicine and Exercise srl, Medical Partner Scuderia Ferrari, Rome, Italy.
George Emil ManoleMed-Ex, Medicine and Exercise srl, Medical Partner Scuderia Ferrari, Rome, Italy.
Stefano PalermiMed-Ex, Medicine and Exercise srl, Medical Partner Scuderia Ferrari, Rome, Italy.
Massimo VolpeCardiology Unit, Department of Clinical and Molecular Medicine, School of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.
Ferrari (Italy) · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the incidence and clinical significance of impaired cardiorespiratory fitness (CRF) and the association with baseline blood pressure (BP) levels and hypertensive response to exercise (HRE).

methodsA cross-sectional study was conducted on a total sample of 2058 individuals with a mean age of 38 ± 9 years, enrolled for the first time at the Ferrari corporate wellness program "Formula Benessere", including a maximal exercise stress testing (EST). BP and heart rate (HR) values were obtained from EST at rest, during exercise and recovery time. CRF was arbitrarily classified according to estimated VO

resultsOne-hundred and thirty-nine individuals of 2058 (6.7%) showed a moderate CRF reduction assessed by EST. Subjects with elevated resting and/or exercise BP showed a worse CRF than those with normal BP levels, also after the adjustment for age, sex, body mass index, smoking habits, peak SBP and DBP. Seventy-seven individuals (3.7%) showed an HRE during EST, with normal baseline BP levels.

conclusionAbout 7% of a corporate population showed a significantly reduced CRF, assessed by EST. Individuals with lower levels of CRF have higher resting and/or peak exercising BP values after adjusting for co-variables. This study expands the role of EST outside of traditional ischemic CVD evaluation, towards the assessment of reduced CRF and HRE in the general population, as a possible not evaluated CV risk factor.

Indexed as

Cardiorespiratory FitnessCardiovascular DiseasesAdultBlood PressureCross-Sectional StudiesExerciseExercise TestHumansMiddle AgedPhysical FitnessCardiorespiratory fitnessCorporate wellnessExercise stress testingHypertensionHypertensive response to exercise

Identifiers

PMID34822139
OpenAlexW3217371798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.