Evidence map›Paper›PMID 34822000›Full record

ArticleHeart and vessels2022

Proposal criteria of paradoxical low-flow low-gradient aortic stenosis for predicting prognosis in patients undergoing transcatheter aortic valve implantation.

Tomomi Tanino, Kunio Yufu, Takashi Shuto, Hiroki Sato, Masayuki Takano, Yumi Ishii, Shintaro Kira, Shotaro Saito, Hidekazu Kondo, Akira Fukui and 6 more

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Article in Heart and vessels, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Tomomi TaninoDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Kunio YufuDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan. yufukuni@oita-u.ac.jp.ORCID http://orcid.org/0000-0002-9668-7630
Takashi ShutoDepartment of Cardiovascular Surgery, Faculty of Medicine, Oita University, Yufu, Japan.
Hiroki SatoDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Masayuki TakanoDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Yumi IshiiDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Shintaro KiraDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Shotaro SaitoDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Hidekazu KondoDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Akira FukuiDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Tomoko FukudaDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Hidefumi AkiokaDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Yasushi TeshimaDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Tomoyuki WadaDepartment of Cardiovascular Surgery, Faculty of Medicine, Oita University, Yufu, Japan.
Shinji MiyamotoDepartment of Cardiovascular Surgery, Faculty of Medicine, Oita University, Yufu, Japan.
Naohiko TakahashiDepartment of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, Yufu, Oita, 879-5593, Japan.
Oita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParadoxical low-flow, low-gradient (PLF-LG) aortic stenosis (AS) is associated with poor prognosis in patients undergoing transcatheter aortic valve implantation (TAVI). This study aimed to verify the conventional criteria of PLF-LG AS (left ventricular ejection fraction [LVEF] > 50%, mean aortic valve pressure gradient [AVPG] < 40 mm Hg and stroke volume index [SVI] < 35 ml/m MATERIALS AND

methodsA total of 128 consecutive patients who underwent TAVI for AS with LVEF > 50% were enrolled. The primary endpoint was the hospital readmission due to heart failure (HRHF) and the secondary endpoint was all-cause mortality after hospital discharge. The patients were classified by both the conventional criteria of PLF-LG AS and the proposal criteria of PLF-LG AS if mean aortic valve pressure gradient (AVPG) < 40 mmHg and SVI by measuring Simpson's method < cut off value based on the ROC curve for predicting HRHF.

resultsAccording to the conventional criteria, only 6 patients were diagnosed with PLF-LG AS. However, according to the proposal criteria, 16 patients were diagnosed with PLF-LG AS. Fourteen patients developed HRHF during the follow-up period after TAVI. Based on the ROC curves, SVI by measuring Simpson's method (cut off value = 25 ml/m

conclusionsOur results demonstrated that new criteria of PLF-LG AS defined as SVI < 25 ml/m

Indexed as

Transcatheter Aortic Valve ReplacementAortic ValveAortic Valve StenosisHumansMultivariate AnalysisPatient ReadmissionPrognosisRetrospective StudiesSeverity of Illness IndexStroke VolumeTreatment OutcomeVentricular Function, LeftDoppler methodHospital readmission due to heart failureParadoxical low-flow low-gradient aortic stenosisSimpson’s methodStroke volume indexTranscatheter aortic valve implantation

Identifiers

PMID34822000
OpenAlexW3215960577

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.