Evidence map›Paper›PMID 34821958›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2022

The selective 5-HT

William H Powell, Lucy E Annett, Ronan Depoortere, Adrian Newman-Tancredi, Mahmoud M Iravani

Abstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  7. The Serotonin 1A (5-HTCNS drugs · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

William H PowellDepartment of Clinical Pharmaceutical and Biological Science, University of Hertfordshire, Hatfield, UK.
Lucy E AnnettDepartment of Psychology, School of Life and Medical Sciences, College Lane, University of Hertfordshire, Hatfield, AL10 9AB, UK.
Ronan DepoortereNeurolixis SAS, 2 Rue Georges Charpak, 81100, Castres, France.
Adrian Newman-TancrediNeurolixis SAS, 2 Rue Georges Charpak, 81100, Castres, France.
Mahmoud M IravaniDepartment of Clinical Pharmaceutical and Biological Science, University of Hertfordshire, Hatfield, UK. m.iravani@herts.ac.uk.ORCID http://orcid.org/0000-0002-4905-9682
University of Hertfordshire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety is amongst the commonest neuropsychiatric disorders, and there is a large body of evidence to suggest that abnormalities in serotonergic function are involved in its pathogenesis. Several studies have implicated 5-HT

Indexed as

AnimalsAnti-Anxiety AgentsAnxietyBehavior, AnimalDisease Models, AnimalDose-Response Relationship, DrugLocomotionMaleMaze LearningMiceMice, Inbred C57BLPiperidinesPyridinesSerotonin 5-HT1 Receptor AgonistsAnti-Anxiety AgentsbefiradolPiperidinesPyridinesSerotonin 5-HT1 Receptor Agonists5-HT1A receptor agonistAnxietyNLX-112Open fieldPlus mazeSerotonin

Identifiers

PMID34821958
OpenAlexW3217654240

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.