Evidence map›Paper›PMID 34821947›Full record

SynthesisNeuroradiology2022

Revascularization of vertebrobasilar tandem occlusions: a meta-analysis.

Mohamed Nabil Mahmoud, Mohamed M A Zaitoun, Mohamed A Abdalla

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Management of tandem occlusions in acute ischaemic stroke.Therapeutic advances in neurological disorders · 2026
    Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Mohamed Nabil MahmoudDepartment of Neurosurgery, Faculty of Medicine, Menoufia University, Shebin El-kom, Menoufia, Egypt. mohamed.nabil@med.menofia.edu.eg.ORCID http://orcid.org/0000-0003-2667-4874
Mohamed M A ZaitounDepartment of Radiology, Faculty of Human Medicine, Zagazig University, Zagazig, Egypt.ORCID http://orcid.org/0000-0003-1317-2955
Mohamed A AbdallaNeurosurgery Department, St George's University Hospital, Blackshaw Road, London, UK.ORCID http://orcid.org/0000-0002-1889-5055
Menoufia University · EGSt George's Hospital · GBZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the difference in mechanical thrombectomy (MT) outcomes between vertebrobasilar tandem occlusion (VBTO) and isolated basilar artery (BA) occlusion (non-VBTO) and the difference in rates of successful recanalization between the clean-road and dirty-road pathways, in VBTO.

methodsWe conducted a meta-analysis after searching PubMed, EMBASE, and Google Scholar databases as of April 2021. We only included adult patients who underwent MT to treat acute ischemic stroke (AIS) due to VBTO, and the following outcomes should be reported: successful recanalization, functional outcome at 90 days, and symptomatic intracerebral hemorrhage (sICH). The main effect size measures were odds ratio and risk difference, and the software used was RevMan 5.4.

resultsThe analysis included 81 VBTO and 324 non-VBTO patients (seven studies). We found no significant difference regarding 3 m functional independence [4 studies: OR = 1.71 (95% CI, 0.54, 5.43), I

conclusionThe results of this meta-analysis support the use of MT for AIS patients with VBTO. In VBTO patients, none of the clean-road or dirty-road pathways proved to be superior to the other.

Indexed as

Brain IschemiaIschemic StrokeStrokeAdultBasilar ArteryHumansThrombectomyTreatment OutcomeStrokeTandem lesionThrombectomyVertebrobasilar

Identifiers

PMID34821947
OpenAlexW3216140071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.