Evidence map›Paper›PMID 34821787›Full record

ArticleInsects2021

A Yeast RNA-Interference Pesticide Targeting the

Keshava Mysore, Longhua Sun, Limb K Hapairai, Chien-Wei Wang, Jessica Igiede, Joseph B Roethele, Nicholas D Scheel, Max P Scheel, Ping Li, Na Wei and 2 more

Open access · goldAbstract read
In one paragraph

Article in Insects, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  10. Article
  11. Outlook on RNAi-Based Strategies for ControllingPathogens (Basel, Switzerland) · 2023
    Review
  12. Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 2 countries.

Keshava MysoreDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN 46617, USA.ORCID 0000-0003-2794-7029
Longhua SunDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN 46617, USA.
Limb K HapairaiDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN 46617, USA.
Chien-Wei WangEck Institute for Global Health, The University of Notre Dame, Notre Dame, IN 46556, USA.
Jessica IgiedeEck Institute for Global Health, The University of Notre Dame, Notre Dame, IN 46556, USA.
Joseph B RoetheleDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN 46617, USA.
Nicholas D ScheelEck Institute for Global Health, The University of Notre Dame, Notre Dame, IN 46556, USA.
Max P ScheelDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN 46617, USA.
Ping LiDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN 46617, USA.
Na WeiEck Institute for Global Health, The University of Notre Dame, Notre Dame, IN 46556, USA.
David W SeversonDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN 46617, USA.ORCID 0000-0002-5798-3365
Molly Duman-ScheelDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Raclin-Carmichael Hall, 1234 Notre Dame Ave., South Bend, IN 46617, USA.ORCID 0000-0003-1254-5369
University of Notre Dame · US

Funding

Development of Yeast Interfering RNA Larvicides Targeting Aedes aegyptiR21AI128116 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SCHEEL, MOLLY DUMAN, SEVERSON, DAVID W · 2017 to 2018
$444k
Innovative Vector Control Consortium N/ANIH/NIAID 1 R21 AI128116-01Showalter Scholar N/AUnited States Department of Defense W81XWH-17-1-0294United States Department of Defense W81XWH-17-1-0295United States Department of Defense W81XWH2120038United States Department of the Army W911QY-17-1-0002
6 · The paper itself

Abstract

Concerns for widespread insecticide resistance and the unintended impacts of insecticides on nontarget organisms have generated a pressing need for mosquito control innovations. A yeast RNAi-based insecticide that targets a conserved site in mosquito

Indexed as

Aedes aegyptiAedes albopictusAnopheles gambiaeATSBCulex quinquefasciatusinsecticideIroquoismosquitoRNAiSaccharomyces cerevisiaeyeast

Identifiers

PMID34821787
PMCPMC8622680
OpenAlexW3210218271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.