Evidence map›Paper›PMID 34821683›Full record

ArticleBiosensors2021

Label-free Surface Enhanced Raman Scattering (SERS) on Centrifugal Silver Plasmonic Paper (CSPP): A Novel Methodology for Unprocessed Biofluids Sampling and Analysis.

Alessandro Esposito, Alois Bonifacio, Valter Sergo, Stefano Fornasaro

Abstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Fabrication and Evaluation of Plasmonic Nanopipettes for Near-Field Enhanced Raman Spectroscopy.Journal of vacuum science & technology. A, Vacuum, surfaces, and films : an official journal of the American Vacuum Society · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alessandro EspositoRaman Spectroscopy Lab, Department of Engineering and Architecture, University of Trieste, 34100 Trieste, Italy.
Alois BonifacioRaman Spectroscopy Lab, Department of Engineering and Architecture, University of Trieste, 34100 Trieste, Italy.ORCID 0000-0002-2251-7786
Valter SergoRaman Spectroscopy Lab, Department of Engineering and Architecture, University of Trieste, 34100 Trieste, Italy.
Stefano FornasaroRaman Spectroscopy Lab, Department of Engineering and Architecture, University of Trieste, 34100 Trieste, Italy.ORCID 0000-0003-3057-7559

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Label-free SERS is a powerful bio-analytical technique in which molecular fingerprinting is combined with localized surface plasmons (LSPs) on metal surfaces to achieve high sensitivity. Silver and gold colloids are among the most common nanostructured substrates used in SERS, but since protein-rich samples such as serum or plasma can hinder the SERS effect due to protein-substrate interactions, they often require a deproteinization step. Moreover, SERS methods based on metal colloids often suffer from a poor reproducibility. Here, we propose a paper-based SERS sampling method in which unprocessed human serum samples are first soaked on paper strips (0.4 × 2 cm

Indexed as

Metal NanoparticlesSilverSpectrum Analysis, RamanColloidsHumansReproducibility of ResultsSerumColloidsSilverbiofluidslabel-free SERSplasmonic paperserumvibrational spectroscopy

Identifiers

PMID34821683
PMCPMC8615985

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.