Evidence map›Paper›PMID 34821641›Full record

ArticleBiosensors2021

OralDisk: A Chair-Side Compatible Molecular Platform Using Whole Saliva for Monitoring Oral Health at the Dental Practice.

Desirée Baumgartner, Benita Johannsen, Mara Specht, Jan Lüddecke, Markus Rombach, Sebastian Hin, Nils Paust, Felix von Stetten, Roland Zengerle, Christopher Herz and 20 more

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 8 institutions in 6 countries.

Desirée BaumgartnerHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Benita JohannsenHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Mara SpechtHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Jan LüddeckeHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Markus RombachHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Sebastian HinHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Nils PaustHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Felix von StettenHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.ORCID 0000-0002-8547-0495
Roland ZengerleHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.
Christopher HerzAIT Austrian Institute of Technology, Molecular Diagnostics, Giefinggasse 4, 1210 Wien, Austria.
Johannes R PehamAIT Austrian Institute of Technology, Molecular Diagnostics, Giefinggasse 4, 1210 Wien, Austria.ORCID 0000-0003-1381-2545
Pune N PaquéClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.ORCID 0000-0002-4219-3395
Thomas AttinClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.
Joël S JenzerClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.ORCID 0000-0002-0590-6894
Philipp KörnerClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.
Patrick R SchmidlinClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.ORCID 0000-0002-1377-0325
Thomas ThurnheerClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.ORCID 0000-0002-8615-8209
Florian J WegehauptClinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland.ORCID 0000-0002-3972-0561
Wendy E KamanDepartment of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre Rotterdam (Erasmus MC), 3015 CN Rotterdam, The Netherlands.
Andrew StubbsDepartment of Pathology and Clinical Bioinformatics, Erasmus University Medical Centre Rotterdam (Erasmus MC), 3015 CN Rotterdam, The Netherlands.ORCID 0000-0001-9817-9982
John P HaysDepartment of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre Rotterdam (Erasmus MC), 3015 CN Rotterdam, The Netherlands.ORCID 0000-0001-9183-4497
Viorel RusuMagtivio B.V., Daelderweg 9, 6361 HK Nuth, The Netherlands.
Alex MichieClinicaGeno Ltd., 11 Station Approach, Coulsdon CR5 2NR, UK.
Thomas BinslClinicaGeno Ltd., 11 Station Approach, Coulsdon CR5 2NR, UK.
David StejskalDepartment of Biomedical Sciences, Faculty of Medicine, University of Ostrava, Syllabova 19, 70300 Ostrava, Czech Republic.
Michal KarpíšekBioVendor-Laboratorní Medicína a.s., Research & Diagnostic Products Division, Karasek 1767/1, Reckovice, 62100 Brno, Czech Republic.ORCID 0000-0001-6503-4250
Kai BaoSection of Oral Health and Periodontology, Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, 14104 Huddinge, Sweden.
Nagihan BostanciSection of Oral Health and Periodontology, Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, 14104 Huddinge, Sweden.
Georgios N BelibasakisSection of Oral Health and Periodontology, Division of Oral Diseases, Department of Dental Medicine, Karolinska Institutet, 14104 Huddinge, Sweden.ORCID 0000-0002-8164-0653
Konstantinos MitsakakisHahn-Schickard, Georges-Koehler-Allee 103, 79110 Freiburg, Germany.ORCID 0000-0002-3287-9123
University of Zurich · CHHahn-Schickard-Gesellschaft für angewandte Forschung · DEUniversity of Freiburg · DEErasmus MC · NLKarolinska Institutet · SEAustrian Institute of Technology · ATMasaryk University · CZUniversity of Ostrava · CZ

Funding

European Commission 633780
6 · The paper itself

Abstract

Periodontitis and dental caries are two major bacterially induced, non-communicable diseases that cause the deterioration of oral health, with implications in patients' general health. Early, precise diagnosis and personalized monitoring are essential for the efficient prevention and management of these diseases. Here, we present a disk-shaped microfluidic platform (OralDisk) compatible with chair-side use that enables analysis of non-invasively collected whole saliva samples and molecular-based detection of ten bacteria: seven periodontitis-associated (

Indexed as

Dental CariesMicrofluidic Analytical TechniquesOral HealthPeriodontitisHumansSalivacariesdental practiceoral healthperiodontitispoint-of-care diagnosticssaliva diagnosticstreatment monitoring

Identifiers

PMID34821641
PMCPMC8615610
OpenAlexW3210467477

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.