Evidence map›Paper›PMID 34821595›Full record

ArticleDentistry journal2021

Influence of the Use of a Collagen Membrane Placed on the Bone Window after Sinus Floor Augmentation-An Experimental Study in Rabbits.

Alessandro Perini, Jose Viña-Almunia, Carmen Carda, José Javier Martín de Llano, Daniele Botticelli, Miguel Peñarrocha-Diago

Open access · goldAbstract read
In one paragraph

Article in Dentistry journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alessandro PeriniDepartment of Neurosciences, Division of Dentistry, University of Padua, 35122 Padua, Italy.
Jose Viña-AlmuniaDepartment of Stomatology, Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0003-4324-4550
Carmen CardaDepartment of Pathology and Health Research Institute of the Hospital Clínico (INCLIVA), Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.
José Javier Martín de LlanoDepartment of Pathology and Health Research Institute of the Hospital Clínico (INCLIVA), Faculty of Medicine and Dentistry, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0001-5933-9592
Daniele BotticelliARDEC Academy, 47923 Rimini, Italy.ORCID 0000-0003-2804-1632
Miguel Peñarrocha-DiagoDepartment of Neurosciences, Division of Dentistry, University of Padua, 35122 Padua, Italy.
Universitat de València · ESUniversity of Padua · IT

Funding

ARDEC Academy, Rimini, Italy NA
6 · The paper itself

Abstract

backgroundWe studied the influence on healing of a resorbable membrane covering the osteotomy site after maxillary sinus grafting, evaluated in different regions of the augmented area.

methodsMaxillary sinus augmentation was performed in 24 New Zealand rabbits. Osteotomy, 4 × 6 mm, were performed bilaterally. A collagenated cortico-cancellous porcine bone was used to fill the elevated region. A collagen membrane was randomly placed over the osteotomy site on one side (MG), and the other side was left uncovered (NMG). The animals were euthanized after 2, 4, and 8 weeks; and histomorphometric analysis was performed in eight different regions.

resultsNew bone percentages were similar in both groups. There were no statistically significant differences. In MG, the overall percentages were 15.6 ± 7.3%, 22.9 ± 6.1%, and 24.9 ± 12.0% after 2, 4, and 8 weeks, respectively. In NMG, the percentages were 11.2 ± 4.5%, 24.1 ± 5.7%, and 24.5 ± 15.7%, respectively. The proportions of new bone in the various regions after 8 weeks were 31 ± 8.9% and 29.9 ± 9.1% in the bone walls region, 25 ± 10.1% and 32.8 ± 9.1% in the submucosa region, 22.6 ± 21.6% and 10.9 ± 11.5 in the middle region, 17.3 ± 14% and 13.4 ± 9.8% in the close-to-window region, and 21.8 ± 11.6%, 19.1 ± 6.4% in the osteotomy region-for MG and NMG, respectively.

conclusionsIn both groups the greatest amounts of bone formation occurred near to the pre-existing bone walls, followed by the sub-mucosa region. The smallest amounts were found in the close-to-window region, followed by the central region. The placement of a collagen membrane to cover the osteotomy site did not influence the amount of new bone formation after sinus grafting.

Indexed as

animal studyantrostomybone healingcollagen membranehistologymorphometryosteoconductivitysinus floor elevationxenograft

Identifiers

PMID34821595
PMCPMC8623347
OpenAlexW3211882014

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.