Evidence map›Paper›PMID 34821591›Full record

ArticleDentistry journal2021

Novel Histomorphometrical Approach to Evaluate the Integration Pattern and Functionality of Barrier Membranes.

Nicola Ottenbacher, Said Alkildani, Tadas Korzinskas, Jens Pissarek, Christian Ulm, Ole Jung, Bernd Sundag, Olaf Bellmann, Sanja Stojanovic, Stevo Najman and 2 more

Open access · goldAbstract read
In one paragraph

Article in Dentistry journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Alveolar Bone Reconstruction Simultaneous to Implant Removal due to Advanced Peri-Implantitis Defects: A Proof of Concept.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Low-temperatureIn vivo (Athens, Greece)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Nicola OttenbacherClinical Division of Oral Surgery, Dental University Clinic, Medical University of Vienna, 1090 Vienna, Austria.
Said AlkildaniBerlinAnalytix GmbH, 12109 Berlin, Germany.ORCID 0000-0002-2629-4102
Tadas KorzinskasBerlinAnalytix GmbH, 12109 Berlin, Germany.
Jens PissarekBiotrics Bioimplants AG, 12109 Berlin, Germany.
Christian UlmClinical Division of Oral Surgery, Dental University Clinic, Medical University of Vienna, 1090 Vienna, Austria.
Ole JungClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, 18057 Rostock, Germany.ORCID 0000-0001-8005-2916
Bernd SundagClinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, 18057 Rostock, Germany.
Olaf BellmannResearch Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.
Sanja StojanovicScientific Research Center for Biomedicine, Department for Cell and Tissue Engineering, Faculty of Medicine, University of of Niš, 18000 Niš, Serbia.
Stevo NajmanScientific Research Center for Biomedicine, Department for Cell and Tissue Engineering, Faculty of Medicine, University of of Niš, 18000 Niš, Serbia.ORCID 0000-0002-2411-9802
Werner ZechnerClinical Division of Oral Surgery, Dental University Clinic, Medical University of Vienna, 1090 Vienna, Austria.ORCID 0000-0002-4142-9992
Mike BarbeckDepartment of Ceramic Materials, Chair of Advanced Ceramic Materials, Institute for Materials Science and Technologies, Technical University Berlin, 10623 Berlin, Germany.ORCID 0000-0002-3001-1347
Medical University of Vienna · ATUniversity of Nis · RSUniversity of Rostock · DEAustrian Cluster for Tissue Regeneration · ATResearch Institute for Farm Animal Biology (FBN) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GBR (guided bone regeneration) is a standard procedure for building up bony defects in the jaw. In this procedure, resorbable membranes made of bovine and porcine collagen are increasingly being used, which, in addition to many possible advantages, could have the potential disadvantage of a shorter barrier functionality, especially when augmenting large-volume defects. Thus, it is of importance to evaluate the integration behavior and especially the standing time of barrier membranes using specialized methods to predict its respective biocompatibility. This study is intended to establish a new histomorphometrical analysis method to quantify the integration rate of collagen-based barrier membranes. Three commercially available barrier membranes, i.e., non-crosslinked membranes (BioGide

Indexed as

barrier membranesbiomaterial integrationcellular immigrationcollagenguided bone regeneration (GBR)histomorphometrical analysishyaluronic acid

Identifiers

PMID34821591
PMCPMC8618445
OpenAlexW3209530658

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.