Evidence map›Paper›PMID 34821138›Full record

ArticleRadiology and oncology2021

Verification of an optimizer algorithm by the beam delivery evaluation of intensity-modulated arc therapy plans.

Tamas Pocza, Domonkos Szegedi, Tibor Major, Csilla Pesznyak

Abstract read
In one paragraph

Article in Radiology and oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tamas PoczaCenter of Radiotherapy, National Institute of Oncology, Budapest, Hungary.
Domonkos SzegediCenter of Radiotherapy, National Institute of Oncology, Budapest, Hungary.
Tibor MajorCenter of Radiotherapy, National Institute of Oncology, Budapest, Hungary.
Csilla PesznyakCenter of Radiotherapy, National Institute of Oncology, Budapest, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the case of dynamic radiotherapy plans, the fractionation schemes can have dosimetric effects. Our goal was to define the effect of the fraction dose on the plan quality and the beam delivery. MATERIALS AND

methodsTreatment plans were created for 5 early-stage lung cancer patients with different dose schedules. The planned total dose was 60 Gy, fraction dose was 2 Gy, 3 Gy, 5 Gy, 12 Gy and 20 Gy. Additionally renormalized plans were created by changing the prescribed fraction dose after optimization. The dosimetric parameters and the beam delivery parameters were collected to define the plan quality and the complexity of the treatment plans. The accuracy of dose delivery was verified with dose measurements using electronic portal imaging device (EPID).

resultsThe plan quality was independent from the used fractionation scheme. The fraction dose could be changed safely after the optimization, the delivery accuracy of the treatment plans with changed prescribed dose was not lower. According to EPID based measurements, the high fraction dose and dose rate caused the saturation of the detector, which lowered the gamma passing rate. The aperture complexity score, the gantry speed and the dose rate changes were not predicting factors for the gamma passing rate values.

conclusionsThe plan quality and the delivery accuracy are independent from the fraction dose, moreover the fraction dose can be changed safely after the dose optimization. The saturation effect of the EPID has to be considered when the action limits of the quality assurance system are defined.

Indexed as

AlgorithmsRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedHumansRadiometryRadiotherapy DosageReproducibility of Resultsdose optimizationfractionation schemeplan normalizationtreatment planning system

Identifiers

PMID34821138
PMCPMC8647790

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