Evidence map›Paper›PMID 34821086›Full record

ArticleZoological research2022

Unexpected expression of heat-activated transient receptor potential (TRP) channels in winter torpid bats and cold-activated TRP channels in summer active bats.

Yang-Yang Li, Qing-Yun Lv, Guan-Tao Zheng, Di Liu, Ji Ma, Gui-Mei He, Li-Biao Zhang, Shan Zheng, Hai-Peng Li, Yi-Hsuan Pan

Open access · diamondAbstract read
In one paragraph

Article in Zoological research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Features and mechanisms of long-livedZoological research · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yang-Yang LiKey Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, School of Life Sciences, East China Normal University, Shanghai 200062, China.
Qing-Yun LvKey Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, School of Life Sciences, East China Normal University, Shanghai 200062, China.
Guan-Tao ZhengKey Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, School of Life Sciences, East China Normal University, Shanghai 200062, China.
Di LiuKey Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, School of Life Sciences, East China Normal University, Shanghai 200062, China.
Ji MaSchool of Life Science, Department of Biomedical Science, East China Normal University, Shanghai 200062, China.
Gui-Mei HeInstitute of Eco-Chongming, School of Life Sciences, East China Normal University, Shanghai 200062, China.
Li-Biao ZhangGuangdong Key Laboratory of Animal Conservation and Resource Utilization, Guangdong Public Laboratory of Wild Animal Conservation and Utilization, Institute of Zoology, Guangdong Academy of Sciences, Guangzhou, Guangdong 510260, China.
Shan ZhengKey Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, School of Life Sciences, East China Normal University, Shanghai 200062, China.
Hai-Peng LiCAS Key Laboratory of Computational Biology, Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, Shanghai 200031, China. E-mail: yihsuanp@gmail.com.
Yi-Hsuan PanKey Laboratory of Brain Functional Genomics of Shanghai and Ministry of Education, School of Life Sciences, East China Normal University, Shanghai 200062, China. E-mail:lihaipeng@picb.ac.cn.
East China Normal University · CNGuangdong Academy of Sciences · CNShanghai Institute of Nutrition and Health · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to sense temperature changes is crucial for mammalian survival. Mammalian thermal sensing is primarily carried out by thermosensitive transient receptor potential channels (Thermo-TRPs). Some mammals hibernate to survive cold winter conditions, during which time their body temperature fluctuates dramatically. However, the underlying mechanisms by which these mammals regulate thermal responses remain unclear. Using quantitative real-time polymerase chain reaction (qRT-PCR) and the Western blotting, we found that

Indexed as

ChiropteraHot TemperatureSeasonsTRPC Cation ChannelsAnimalsFemaleHibernationMaleMiceTRPV Cation ChannelsTRPC Cation ChannelsTRPV Cation ChannelsBatsBrainHibernationThermo-TRPs

Identifiers

PMID34821086
PMCPMC8743255
OpenAlexW3214371481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.