Evidence map›Paper›PMID 34820848›Full record

ArticleAllergy2022

Mast cell activation is associated with post-acute COVID-19 syndrome.

Joshua B Wechsler, Melina Butuci, Alan Wong, Amol P Kamboj, Bradford A Youngblood

Open access · hybridAbstract readLetter
In one paragraph

Article in Allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 4 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 4 syntheses or guidelines pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. The Central Role of Macrophages in Long COVID Pathophysiology.International journal of molecular sciences · 2025
    Review
  14. Diagnosis and management of mast cell activation syndrome (MCAS) in Canada: a practical approach.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Review
  15. Article
  16. Review
  17. Article
  18. Inflammatory pathways in patients with post-acute sequelae of COVID-19: The role of the clinical immunologist.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Joshua B WechslerNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Melina ButuciAllakos, Inc., Redwood City, California, USA.
Alan WongAllakos, Inc., Redwood City, California, USA.
Amol P KambojAllakos, Inc., Redwood City, California, USA.ORCID 0000-0003-3611-7326
Bradford A YoungbloodAllakos, Inc., Redwood City, California, USA.
Allakos (United States) · USNorthwestern University · US

Funding

Allakos, Inc
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19CytokinesHumansImmunity, InnateInflammationMast CellsPost-Acute COVID-19 SyndromeCytokinesCOVIDinflammationinnate immunitylong covidmast cells

Identifiers

PMID34820848
PMCPMC9299596
OpenAlexW3215022270

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.