Evidence map›Paper›PMID 34820842›Full record

ArticleThe Journal of physiology2022

ATP-sensitive potassium channels in zebrafish cardiac and vascular smooth muscle.

Soma S Singareddy, Helen I Roessler, Conor McClenaghan, Jennifer M Ikle, Robert C Tryon, Gijs van Haaften, Colin G Nichols

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Gold nanoparticle-based colorimetric detection of ATP via a label-free aptamer.Frontiers in bioengineering and biotechnology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KThe Journal of pharmacology and experimental therapeutics · 2023
    Article
  6. CaInternational journal of molecular sciences · 2023
    Review
  7. Kir6.1 and SUR2B in Cantú syndrome.American journal of physiology. Cell physiology · 2022
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Soma S SingareddyDepartment of Cell Biology and Physiology and Center for the Investigation of Membrane Excitability Diseases, Washington University in St Louis, St Louis, MO, USA.
Helen I RoesslerDepartment of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Conor McClenaghanDepartment of Cell Biology and Physiology and Center for the Investigation of Membrane Excitability Diseases, Washington University in St Louis, St Louis, MO, USA.
Jennifer M IkleDepartment of Cell Biology and Physiology and Center for the Investigation of Membrane Excitability Diseases, Washington University in St Louis, St Louis, MO, USA.
Robert C TryonDepartment of Cell Biology and Physiology and Center for the Investigation of Membrane Excitability Diseases, Washington University in St Louis, St Louis, MO, USA.
Gijs van HaaftenDepartment of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Colin G NicholsDepartment of Cell Biology and Physiology and Center for the Investigation of Membrane Excitability Diseases, Washington University in St Louis, St Louis, MO, USA.ORCID 0000-0002-4929-2134
Washington University in St. Louis · USUtrecht University · NL

Funding

Role of vascular KATP channels in Alzheimer’s neurodegeneration and dementiaR35HL140024 · NHLBI · WASHINGTON UNIVERSITY · PI NICHOLS, COLIN G · 2018 to 2023
$5.9M
Electrical excitability in vascular smooth muscle: from rare disease to new paradigmsR00HL150277 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI MCCLENAGHAN, CONOR · 2022 to 2024
$747k
Electrical excitability in vascular smooth muscle: from rare disease to new paradigmsK99HL150277 · NHLBI · WASHINGTON UNIVERSITY · PI MCCLENAGHAN, CONOR · 2020 to 2021
$200k
NHLBI NIH HHS K99 HL150277NHLBI NIH HHS R00 HL150277NHLBI NIH HHS R35 HL140024
6 · The paper itself

Abstract

ATP-sensitive potassium channels (K

Indexed as

HypertrichosisKATP ChannelsAnimalsHumansMuscle, Smooth, VascularMyocytes, CardiacSulfonylurea ReceptorsZebrafishKATP ChannelsSulfonylurea ReceptorsABCC9Cantú syndromecardiomyocytescardiovascularion channelsKATPKCNJ8Kir6.2SUR2vascular smooth muscle cellszebrafish

Identifiers

PMID34820842
PMCPMC9764990
OpenAlexW3215617387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.