Evidence map›Paper›PMID 34820660›Full record

ArticleCell genomics2021

GA4GH Passport standard for digital identity and access permissions.

Craig Voisin, Mikael Linden, Stephanie O M Dyke, Sarion R Bowers, Pinar Alper, Maxmillian P Barkley, David Bernick, Jianpeng Chao, Mélanie Courtot, Francis Jeanson and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
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  5. The Portuguese Beacon: sharing genomic variant data safely.Database : the journal of biological databases and curation · 2026
    Article
  6. Review
  7. Article
  8. Article
  9. Review
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  11. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Craig VoisinGoogle LLC, Kitchener, ON N2H 5G5, Canada.
Mikael LindenCSC-IT Center for Science, Espoo 02101, Finland.
Stephanie O M DykeMcGill Centre for Integrative Neuroscience, McGill University, Montreal, QC H3A 2B4, Canada.
Sarion R BowersWellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Pinar AlperELIXIR Luxembourg, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, 4367 Belvaux, Luxembourg.
Maxmillian P BarkleyDNAstack, Toronto, ON M5H 1T1, Canada.
David BernickBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Jianpeng ChaoGoogle LLC, Kitchener, ON N2H 5G5, Canada.
Mélanie CourtotEuropean Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire CB10 1SD, UK.
Francis JeansonDatadex Inc., Toronto, ON M5V 0C4, Canada.
Melissa A KonopkoWellcome Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Martin KubaMasaryk University, Brno 602 00, Czech Republic.
Jonathan LawsonBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Jaakko LeinonenCSC-IT Center for Science, Espoo 02101, Finland.
Stephanie LiBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Vivian Ota WangNational Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Anthony A PhilippakisBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Kathy ReinoldBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
Gregory A RushtonBroad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
J Dylan SpaldingCSC-IT Center for Science, Espoo 02101, Finland.
Juha TörnroosCSC-IT Center for Science, Espoo 02101, Finland.
Ilya TulchinskyVerily Life Sciences, South San Francisco, CA 94080, USA.
Jaime M Guidry AuvilNational Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Tommi H NyrönenCSC-IT Center for Science, Espoo 02101, Finland.

Funding

The AnVIL Data Ecosystem DACReS SupplementU24HG010262 · NHGRI · BROAD INSTITUTE, INC. · PI Robert J Carroll, Jonathan Lawson · 2018 to 2026
$40.5M
NHGRI NIH HHS U24 HG010262Wellcome Trust
6 · The paper itself

Abstract

The Global Alliance for Genomics and Health (GA4GH) supports international standards that enable a federated data sharing model for the research community while respecting data security, ethical and regulatory frameworks, and data authorization and access processes for sensitive data. The GA4GH Passport standard (Passport) defines a machine-readable digital identity that conveys roles and data access permissions (called "visas") for individual users. Visas are issued by data stewards, including data access committees (DACs) working with public databases, the entities responsible for the quality, integrity, and access arrangements for the datasets in the management of human biomedical data. Passports streamline management of data access rights across data systems by using visas that present a data user's digital identity and permissions across organizations, tools, environments, and services. We describe real-world implementations of the GA4GH Passport standard in use cases from ELIXIR Europe, National Institutes of Health, and the Autism Sharing Initiative. These implementations demonstrate that the Passport standard has provided transparent mechanisms for establishing permissions and authorizing data access across platforms.

Indexed as

accessauthorizationdatafederationgenomicsidentityinfrastructureregulationsecuritystandard

Identifiers

PMID34820660
PMCPMC8591913

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.