Evidence map›Paper›PMID 34820364›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Design of Porous Metal Block Augmentation to Treat Tibial Bone Defects in Total Knee Arthroplasty Based on Topology Optimization.

Yang Liu, Bingpeng Chen, Chenyu Wang, Hao Chen, Aobo Zhang, Weihuang Yin, Naichao Wu, Qing Han, Jincheng Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. [Effects of elastic modulus of the metal block on the condylar-constrained knee prosthesis tibial fixation stability].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yang LiuDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Bingpeng ChenDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Chenyu WangDepartment of Plastic and Reconstructive Surgery, First Bethune Hospital of Jilin University, Changchun, China.
Hao ChenDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Aobo ZhangDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Weihuang YinDepartment of Oral and Maxillofacial Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Naichao WuDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Qing HanDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Jincheng WangDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Second Affiliated Hospital of Jilin University · CNFirst Bethune Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metal block augmentation, which is used for the treatment of tibial bone defects in total knee arthroplasty, with high stiffness will cause significant alteration in stress distribution, and its solid structure is not suitable for osseointegration. This study aimed to design a porous block to reduce weight, promote bone ingrowth, and improve its biomechanical performance. The metal block augmentation technique was applied to finite element models of tibial bone defects. Minimum compliance topology optimization subject to volume fraction combined with the porous architecture was adopted to redesign the block. Biomechanical changes compared with the original block were analyzed by finite element analysis. The stress distribution of the block and proximal tibia was recorded. The strain energy density of the proximal tibia was obtained. The newly designed block realized 40% weight reduction. The maximum stress in the optimized block decreased by 11.6% when compared with the solid one. The maximum stress of the proximal tibia in the optimized group increased by 18.6%. The stress of the anterior, medial, and posterior parts of the proximal medial tibia in the optimized group was significantly greater than that in the original group (all

Indexed as

bone defectfinite element analysismetal block augmentationtopology optimizationtotal knee arthroplasty

Identifiers

PMID34820364
PMCPMC8606634
OpenAlexW3212487508

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.