Evidence map›Paper›PMID 34820312›Full record

ArticleJournal of advanced pharmaceutical technology & research

Characterization and cytotoxicity of low-molecular-weight chitosan and chito-oligosaccharides derived from tilapia fish scales.

Gul-E-Saba Chaudhry, C S Thirukanthan, K Murni NurIslamiah, Y Y Sung, T S M Sifzizul, A W M Effendy

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced pharmaceutical technology & research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Gul-E-Saba ChaudhryInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Malaysia.
C S ThirukanthanInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Malaysia.
K Murni NurIslamiahInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Malaysia.
Y Y SungInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Malaysia.
T S M SifzizulInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Malaysia.
A W M EffendyInstitute of Marine Biotechnology, Universiti Malaysia Terengganu, Malaysia.
Universiti Malaysia Terengganu · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study evaluated the physicochemical characterization and cytotoxicity activity of chitosan and chito-oligosaccharides (COSs). The extraction of chitosan and COSs was executed by chemical hydrolysis. The physicochemical characterization and deacetylation (DA) value were determined using an FTIR. The molecular weight was determined by using the Mark-Houwink equation. The physical parameters such as solubility, water-binding capacity (WBC), and fat-binding capacity (FBC) were determination as per equation (i), (ii), and (iii) respectively. The cytotoxic activities of chitosan and COS against MCF-7, HepG2, HeLa-6, and 3T3 were performed by MTS assay. The COS induced enhance cytotoxicity with IC

Indexed as

Biodegradable polymercancerchito-oligosaccharideschitosancytotoxicityMTS

Identifiers

PMID34820312
PMCPMC8588928
OpenAlexW3206143089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.