Evidence map›Paper›PMID 34820240›Full record

ArticleCureus2021

A Case of Idiopathic Thrombocytopenic Purpura After Booster Dose of BNT162b2 (Pfizer-Biontech) COVID-19 Vaccine.

Srikrishna V Malayala, Bhavani N Papudesi, Rishika Sharma, Urwat T Vusqa, Ambreen Raza

Abstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. A Case of COVID-19 Induced Descending Aortic Thrombus and Splenic Infarctions.Journal of community hospital internal medicine perspectives · 2022
    Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Srikrishna V MalayalaInternal Medicine, Temple University Hospital, Philadelphia, USA.
Bhavani N PapudesiInternal Medicine, Mercy Health, Philadelphia, USA.
Rishika SharmaPediatric Medicine, Kaweah Delta Health Care District, Visalia, USA.
Urwat T VusqaInternal Medicine, Allegheny Health Network, Pittsburgh, USA.
Ambreen RazaInternal Medicine, Bayhealth Hospital, Dover, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination is now considered the best measure in minimizing the morbidity and mortality from the Covid-19 pandemic. Almost all the vaccines are considered safe except for minor and occasional side effects. Some of the commonly reported complications from the COVID-19 vaccines are vaccine-induced thrombotic thrombocytopenia (VITT)/thrombosis with thrombocytopenia syndrome/vaccine-induced pro-thrombotic immune thrombocytopenia syndrome. In this case report, we present a case of a 75-year-old female who had an uncomplicated first and second vaccine dose but developed VITT after the booster dose of the vaccine. The patient was treated with dexamethasone and platelet transfusions. So far no such cases have been reported after the third (booster) dose of the Pfizer-Biontech vaccine. With this case report, we present the case of the patient and discuss the literature related to vaccine-induced thrombocytopenia.

Indexed as

booster side effectscovid 19covid-19 vaccinecovid-19 vaccine complicationcovid associated thrombocytopeniadrug-induced itpidiopathic thrombocytopenic purpuramrna-based vaccinepfizer-biontech covid-19 vaccinevaccine side effects

Identifiers

PMID34820240
PMCPMC8607313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.