Evidence map›Paper›PMID 34820153›Full record

ArticleGlobal advances in health and medicine2021

Lavender Aromatherapy to Reduce Anxiety During Intrauterine Insemination: A Randomized Controlled Trial.

Tiffanny Jones, MacKenzie Purdy, Elizabeth A Stewart, Susanne M Cutshall, Matthew A Hathcock, Saswati Mahapatra, Brent A Bauer, Alessandra J Ainsworth

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global advances in health and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06045078 (Aromatherapy for Post-operative Anxiety and Pain After Primary Unilateral Total Knee Replacement), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06045078 nacompletednot on this mapstarted 2023, after this paper: background citation

Aromatherapy for Post-operative Anxiety and Pain After Primary Unilateral Total Knee Replacement: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorHospital for Special Surgery, New YorkRan2023 to 2024Enrolled30ConditionsTotal Knee Replacement, Post-operative Nausea and Vomiting, Opioid Use, AnxietyArmsElequil Lavender-peppermint Aromatabs, Elequil Almond-Oil Aromatabs
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tiffanny JonesMayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
MacKenzie PurdyMayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Elizabeth A StewartDivision of Reproductive Endocrinology and Infertility, Mayo Clinic, Rochester, MN, USA.
Susanne M CutshallDivision of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Matthew A HathcockInternal Medicine Administrative Services, Mayo Clinic, Rochester, MN, USA.
Saswati MahapatraDepartment of Research Administration, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0002-6929-1382
Brent A BauerDivision of General Internal Medicine, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0003-3453-6906
Alessandra J AinsworthDivision of Reproductive Endocrinology and Infertility, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · USMayo Clinic · USMayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfertility is a global public health issue. Therapies such as intrauterine insemination (IUI) are effective but may be associated with considerable anxiety. Preliminary data suggest that decreasing this anxiety might lead to improved outcomes.

objectiveTo determine whether lavender aromatherapy (LA) reduces anxiety during an IUI procedure.

methodsA randomized controlled trial of women undergoing IUI at a hospital-based fertility clinic. The intervention and comparison were the use of LA vs water. Measurements were the change in anxiety level during an IUI procedure, with secondary assessment of pain scores, patient satisfaction, and pregnancy rates.

resultsIn total, 67 women were screened, and 62 women randomly assigned to either placebo (n = 31) or LA (n = 31). No differences were observed in baseline demographic characteristics or visual analog scores for anxiety before IUI (mean [95% CI], 33.9 [25.2 to 45.6] mm vs 41.0 [33.0 to 49.0] mm) in the LA and placebo groups. However, a statistically significant change in anxiety was observed after LA inhalation during the procedure (mean [95% CI], -11.2 [-19.1 to -3.2]) compared with placebo (mean [95% CI], 1.3 [-5.6 to 8.2];

conclusionLA reduced anxiety and was preferred by women during IUI fertility treatments.

Indexed as

anxietyinfertilityintrauterine inseminationlavender aromatherapy

Identifiers

PMID34820153
PMCPMC8606920
OpenAlexW3212253112

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.