Evidence map›Paper›PMID 34820139›Full record

ArticleJournal of nutrition and metabolism2021

Serum Uric Acid Is Associated with Metabolic Syndrome and Insulin Resistance among Health Personnel from Peru.

Brenda M Galindo-Yllu, Ricardo Rojas-Humpire, Carlos J Toro-Huamanchumo, Rosmery Gutierrez-Ajalcriña, Anderson N Soriano

Open access · goldAbstract read
In one paragraph

Article in Journal of nutrition and metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Brenda M Galindo-YlluClinical and Epidemiological Research Unit, School of Medicine, Universidad Peruana Union, Lima, Peru.
Ricardo Rojas-HumpireClinical and Epidemiological Research Unit, School of Medicine, Universidad Peruana Union, Lima, Peru.ORCID https://orcid.org/0000-0002-0631-0902
Carlos J Toro-HuamanchumoUniversidad San Ignacio de Loyola, Unidad para la Generación y Síntesis de Evidencias en Salud, Lima, Peru.
Rosmery Gutierrez-AjalcriñaUnidad de Epidemiología y Salud Ambiental, Hospital de Huaycán, Ate, Peru.
Anderson N SorianoClinical and Epidemiological Research Unit, School of Medicine, Universidad Peruana Union, Lima, Peru.ORCID https://orcid.org/0000-0002-5535-811X
Universidad Peruana Unión · PEHOPE Clinic · USUniversidad San Ignacio de Loyola · PE

Funding

Research training in chronic, non-communicable respiratory diseases in PeruD43TW011502 · FIC · JOHNS HOPKINS UNIVERSITY · PI CHECKLEY, WILLIAM, HARTINGER, STELLA MARIA · 2019 to 2023
$1.2M
FIC NIH HHS D43 TW011502
6 · The paper itself

Abstract

We explored the association between serum uric acid (SUA) and metabolic syndrome (MetS) and insulin resistance (IR) among health personnel from a public hospital in Peru in a cross-sectional study with data from the Plan for the Prevention and Surveillance of Communicable and Noncommunicable Diseases of Huaycán Hospital. MetS was defined according to Latin American Diabetes Association (ALAD) criteria and IR with surrogate IR markers, triglyceride-to-HDL-C ratio (TG/HDL-C), and triglyceride-to-glucose index (TyG). The association between SUA and MetS and IR was determined using Poisson regression models in a sample of 292 participants with an average age of 46.2 ± 10.6 years. The total prevalence of MetS was 38%, and the individuals with MetS presented mainly alterations in anthropometric parameters (obesity and body fat). Finally, the adjusted regression models showed that women with SUA in the highest tertile increased the prevalence of MetS (PR: 1.71, 95% CI: 1.07-2.74) compared to the lowest tertile of SUA in women, while SUA increased hypertriglyceridemia and IR (TG/HDL-C and TyG) in both sexes. We concluded that SUA is strongly associated with MetS in women, and SUA increases hypertriglyceridemia and IR in both sexes. On the contrary, more research is required regarding the female population.

Identifiers

PMID34820139
PMCPMC8608523
OpenAlexW3213062175

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.