Evidence map›Paper›PMID 34819965›Full record

ArticlePostepy w kardiologii interwencyjnej = Advances in interventional cardiology2021

Predictors of mortality following extracorporeal membrane oxygenation support in an unselected, critically ill patient population.

István Ferenc Édes, Balázs Tamás Németh, István Hartyánszky, Bálint Szilveszter, Péter Kulyassa, Levente Fazekas, Miklós Pólos, Endre Németh, Dávid Becker, Béla Merkely

Open access · goldAbstract read
In one paragraph

Article in Postepy w kardiologii interwencyjnej = Advances in interventional cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

István Ferenc ÉdesHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Balázs Tamás NémethHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
István HartyánszkyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Bálint SzilveszterHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Péter KulyassaHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Levente FazekasHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Miklós PólosHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Endre NémethDepartment of Anesthesiology and Intensive Therapy, Semmelweis University, Budapest, Hungary.
Dávid BeckerHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Béla MerkelyHeart and Vascular Center, Semmelweis University, Budapest, Hungary.
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMechanical circulatory support (MCS) has been established as a means of augmenting circulation in patients with critically decreased systolic function due to a variety of underlying clinical reasons. Different methods of MCS may be used, with the venous-arterial extracorporeal membrane oxygenation system (VA-ECMO) being one of the most utilized devices in everyday care.

aimTo determine independent predictors influencing mortality outcomes following VA-ECMO therapy in a large, unselected, adult, critically ill patient population in cardiogenic shock (CS). MATERIAL AND

methodsData on 235 consecutive, real-world VA-ECMO treatments were assessed. Analysis was conducted for all subjects requiring MCS with the VA-ECMO as the first instalment, regardless of underlying cause or eventual upgrade. All potential clinical factors influencing mortality were examined and evaluated.

resultsOverall mortality was ~66% at median 28 days follow-up and significantly depended upon pH < 7.3 (HR = 3.56;

conclusionsMortality in patients requiring VA-ECMO remains high. We conclude that only decreased pH values and advanced age clearly influence mortality in this MCS scenario. ACS also bodes unfavorably, whereas hTX as an indication clearly shows better survival.

Indexed as

mechanical circulatory supportpVA-ECMOsurvival

Identifiers

PMID34819965
PMCPMC8596723
OpenAlexW3200545807

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.